product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 488 anti-human IgM
catalog :
314533
quantity :
25 tests
price :
165 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF488
clone name :
MHM-88
reactivity :
human
application :
flow cytometry, mass cytometry
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2a
Brouwer P, Caniels T, van der Straten K, Snitselaar J, Aldon Y, Bangaru S, et al. Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability. Science. 2020;369:643-650 pubmed publisher
  • mass cytometry; human; 500 ug/ml; loading ...; fig s11a
Helmink B, Reddy S, Gao J, Zhang S, Basar R, Thakur R, et al. B cells and tertiary lymphoid structures promote immunotherapy response. Nature. 2020;577:549-555 pubmed publisher
  • flow cytometry; human; loading ...; fig s6d
Bradley T, Peppa D, Pedroza Pacheco I, Li D, Cain D, Henao R, et al. RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses. Cell. 2018;175:387-399.e17 pubmed publisher
  • flow cytometry; human; loading ...; fig s2a
Dam E, Maier A, Hocking A, Carlin J, Buckner J. Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis. Front Immunol. 2018;9:1978 pubmed publisher
Asrat S, Devlin J, Vecchione A, Klotz B, Setliff I, Srivastava D, et al. TRAPnSeq allows high-throughput profiling of antigen-specific antibody-secreting cells. Cell Rep Methods. 2023;3:100522 pubmed publisher
Fels J, Maurer D, Herbert A, Wirchnianski A, Vergnolle O, Cross R, et al. Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever. Cell. 2021;184:3486-3501.e21 pubmed publisher
Seydoux E, Homad L, MacCamy A, Parks K, Hurlburt N, Jennewein M, et al. Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation. Immunity. 2020;53:98-105.e5 pubmed publisher
Gang E, Kim H, Hsieh Y, Ruan Y, Ogana H, Lee S, et al. Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 2020;136:210-223 pubmed publisher
Franco L, Gadkari M, Howe K, Sun J, Kardava L, Kumar P, et al. Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses. J Exp Med. 2019;216:384-406 pubmed publisher
Baglaenko Y, Chang N, Johnson S, Hafiz W, Manion K, Ferri D, et al. The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic disease. Arthritis Res Ther. 2018;20:264 pubmed publisher
Phelan J, Young R, Webster D, Roulland S, Wright G, Kasbekar M, et al. A multiprotein supercomplex controlling oncogenic signalling in lymphoma. Nature. 2018;560:387-391 pubmed publisher
Setliff I, McDonnell W, Raju N, Bombardi R, Murji A, Scheepers C, et al. Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection. Cell Host Microbe. 2018;23:845-854.e6 pubmed publisher
Sevilla A, Forero E, Zimmer M, Martínez H, Reggio K, Paull D, et al. Derivation and characterization of the NIH registry human stem cell line NYSCF100 line under defined feeder-free conditions. Stem Cell Res. 2018;29:99-102 pubmed publisher
Laksono B, Grosserichter Wagener C, de Vries R, Langeveld S, Brem M, van Dongen J, et al. In Vitro Measles Virus Infection of Human Lymphocyte Subsets Demonstrates High Susceptibility and Permissiveness of both Naive and Memory B Cells. J Virol. 2018;92: pubmed publisher
Blum L, Cao R, Sweatt A, Bill M, Lahey L, Hsi A, et al. Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension. Eur J Immunol. 2018;48:874-884 pubmed publisher
Pinder C, Kratochvil S, Cizmeci D, Muir L, Guo Y, Shattock R, et al. Isolation and Characterization of Antigen-Specific Plasmablasts Using a Novel Flow Cytometry-Based Ig Capture Assay. J Immunol. 2017;199:4180-4188 pubmed publisher
Arkatkar T, Du S, Jacobs H, Dam E, Hou B, Buckner J, et al. B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity. J Exp Med. 2017;214:3207-3217 pubmed publisher
Perez Shibayama C, Gil Cruz C, Pastelin Palacios R, Cervantes Barragan L, Hisaki E, Chai Q, et al. IFN-?-producing CD4+ T cells promote generation of protective germinal center-derived IgM+ B cell memory against Salmonella Typhi. J Immunol. 2014;192:5192-200 pubmed publisher
product information
Antigen :
IgM
Apps. Abbrev. :
FC
Cat # :
314533
Clone :
MHM-88
Item :
Alexa Fluor® 488 anti-human IgM
Isotype :
Mouse IgG1, κ
Other Names :
Immunoglobulin M
Size :
25 tests
Price (USD) :
165 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A488
Immunogen :
Human Ig cocktail
Application Notes :
MHM-88 antibody reacts with both soluble and membrane human immunoglobulin M (IgM). It does not react with other Ig isotypes. Additional reported applications (for the relevant formats) include: use as a primary or secondary reagent for ELISA analysis.Due to the presence of excess soluble IgM in whole blood, which competes for antibody binding, staining for IgM on cells in whole blood is not recommended.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA