product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human IgM
catalog :
314509
quantity :
25 tests
price :
137 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
MHM-88
reactivity :
human
application :
flow cytometry
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:200; loading ...; fig 2f
Zumaquero E, Stone S, Scharer C, Jenks S, Nellore A, Mousseau B, et al. IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation. elife. 2019;8: pubmed publisher
Marsman C, Verhoeven D, Koers J, Rispens T, ten Brinke A, Van Ham S, et al. Optimized Protocols for In-Vitro T-Cell-Dependent and T-Cell-Independent Activation for B-Cell Differentiation Studies Using Limited Cells. Front Immunol. 2022;13:815449 pubmed publisher
Ercanoglu M, Gieselmann L, D xe4 hling S, Poopalasingam N, Detmer S, Koch M, et al. No substantial preexisting B cell immunity against SARS-CoV-2 in healthy adults. iScience. 2022;25:103951 pubmed publisher
Sefik E, Israelow B, Mirza H, Zhao J, Qu R, Kaffe E, et al. A humanized mouse model of chronic COVID-19. Nat Biotechnol. 2021;: pubmed publisher
Feldman J, Bals J, Altomare C, St Denis K, Lam E, Hauser B, et al. Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses. Sci Immunol. 2021;6:eabl5842 pubmed publisher
Deakin C, Cornish G, Ng K, Faulkner N, Bolland W, Hope J, et al. Favorable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases. Med. 2021;2:1093-1109.e6 pubmed publisher
Faulkner N, Ng K, Wu M, Harvey R, Margaritis M, Paraskevopoulou S, et al. Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains. elife. 2021;10: pubmed publisher
Brouwer P, Brinkkemper M, Maisonnasse P, Dereuddre Bosquet N, Grobben M, Claireaux M, et al. Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection. Cell. 2021;184:1188-1200.e19 pubmed publisher
Jongsma M, de Waard A, Raaben M, Zhang T, Cabukusta B, Platzer R, et al. The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses. Immunity. 2021;54:132-150.e9 pubmed publisher
Pellett Madan R, Penkert R, Surman S, Jones B, Houston J, Lamour J, et al. Persistent hypogammaglobulinemia in pediatric solid organ transplant recipients. Clin Transplant. 2020;34:e14021 pubmed publisher
Gang E, Kim H, Hsieh Y, Ruan Y, Ogana H, Lee S, et al. Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 2020;136:210-223 pubmed publisher
Shehata L, Maurer D, Wec A, Lilov A, Champney E, Sun T, et al. Affinity Maturation Enhances Antibody Specificity but Compromises Conformational Stability. Cell Rep. 2019;28:3300-3308.e4 pubmed publisher
Watanabe A, McCarthy K, Kuraoka M, Schmidt A, Adachi Y, Onodera T, et al. Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism. Cell. 2019;177:1124-1135.e16 pubmed publisher
Mclaurin J, Weiner O. Multiple sources of signal amplification within the B-cell Ras/MAPK pathway. Mol Biol Cell. 2019;30:1610-1620 pubmed publisher
Villar R, Patel J, Weaver G, Kanekiyo M, Wheatley A, Yassine H, et al. Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation. Sci Rep. 2016;6:36298 pubmed publisher
Perez Shibayama C, Gil Cruz C, Pastelin Palacios R, Cervantes Barragan L, Hisaki E, Chai Q, et al. IFN-?-producing CD4+ T cells promote generation of protective germinal center-derived IgM+ B cell memory against Salmonella Typhi. J Immunol. 2014;192:5192-200 pubmed publisher
product information
Antigen :
IgM
Apps. Abbrev. :
FC
Cat # :
314509
Clone :
MHM-88
Item :
APC anti-human IgM
Isotype :
Mouse IgG1, κ
Other Names :
Immunoglobulin M
Size :
25 tests
Price (USD) :
137 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
Human Ig cocktail
Application Notes :
MHM-88 antibody reacts with both soluble and membrane human immunoglobulin M (IgM). It does not react with other Ig isotypes. Additional reported applications (for the relevant formats) include: use as a primary or secondary reagent for ELISA analysis.Due to the presence of excess soluble IgM in whole blood, which competes for antibody binding, staining for IgM on cells in whole blood is not recommended.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA