product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-human/mouse CD49f
catalog :
313623
quantity :
25 tests
price :
198 USD
clonality :
monoclonal
host :
rat
conjugate :
BV421
clone name :
GoH3
reactivity :
human, mouse, rhesus macaque
application :
flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse
Goldstein A, Huang J, Guo C, Garraway I, Witte O. Identification of a cell of origin for human prostate cancer. Science. 2010;329:568-71 pubmed publisher
Xiang X, Tao Y, DiRusso J, Hsu F, Zhang J, Xue Z, et al. Human reproduction is regulated by retrotransposons derived from ancient Hominidae-specific viral infections. Nat Commun. 2022;13:463 pubmed publisher
Io S, Kabata M, Iemura Y, Semi K, Morone N, Minagawa A, et al. Capturing human trophoblast development with naive pluripotent stem cells in vitro. Cell Stem Cell. 2021;28:1023-1039.e13 pubmed publisher
Lau K, Mason E, Kie J, De Souza D, Kloehn J, Tull D, et al. Unique properties of a subset of human pluripotent stem cells with high capacity for self-renewal. Nat Commun. 2020;11:2420 pubmed publisher
Chen D, Sun N, Hou L, Kim R, Faith J, Aslanyan M, et al. Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors. Cell Rep. 2019;29:4568-4582.e5 pubmed publisher
Mok K, Saxena N, Heitman N, Grisanti L, Srivastava D, Muraro M, et al. Dermal Condensate Niche Fate Specification Occurs Prior to Formation and Is Placode Progenitor Dependent. Dev Cell. 2019;48:32-48.e5 pubmed publisher
Chen D, Liu W, Zimmerman J, Pastor W, Kim R, Hosohama L, et al. The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation. Cell Rep. 2018;25:3591-3602.e5 pubmed publisher
Sosa E, Chen D, Rojas E, Hennebold J, Peters K, Wu Z, et al. Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. Nat Commun. 2018;9:5339 pubmed publisher
Yamashiro C, Sasaki K, Yabuta Y, Kojima Y, Nakamura T, Okamoto I, et al. Generation of human oogonia from induced pluripotent stem cells in vitro. Science. 2018;362:356-360 pubmed publisher
Evrard M, Kwok I, Chong S, Teng K, Becht E, Chen J, et al. Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions. Immunity. 2018;48:364-379.e8 pubmed publisher
Khoramian Tusi B, Socolovsky M. High-throughput single-cell fate potential assay of murine hematopoietic progenitors in vitro. Exp Hematol. 2018;60:21-29.e3 pubmed publisher
Gell J, Zhao J, Chen D, Hunt T, Clark A. PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. Stem Cell Res. 2018;27:46-56 pubmed publisher
Chen D, Liu W, Lukianchikov A, Hancock G, Zimmerman J, Lowe M, et al. Germline competency of human embryonic stem cells depends on EOMESODERMIN. Biol Reprod. 2017;: pubmed publisher
Kojima Y, Sasaki K, Yokobayashi S, Sakai Y, Nakamura T, Yabuta Y, et al. Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells. Cell Stem Cell. 2017;21:517-532.e5 pubmed publisher
Moriyama M, Moriyama H, Uda J, Kubo H, Nakajima Y, Goto A, et al. Beneficial Effects of the Genus Aloe on Wound Healing, Cell Proliferation, and Differentiation of Epidermal Keratinocytes. PLoS ONE. 2016;11:e0164799 pubmed publisher
Oeztuerk Winder F, Guinot A, Ochalek A, Ventura J. Regulation of human lung alveolar multipotent cells by a novel p38α MAPK/miR-17-92 axis. EMBO J. 2012;31:3431-41 pubmed publisher
Lai K, Yamashita S, Vitkus S, Shyr C, Yeh S, Chang C. Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptor. Mol Endocrinol. 2012;26:52-66 pubmed publisher
Grange C, Tapparo M, Collino F, Vitillo L, Damasco C, Deregibus M, et al. Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Cancer Res. 2011;71:5346-56 pubmed publisher
Jo M, Eastman B, Webb D, Stoletov K, Klemke R, Gonias S. Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Cancer Res. 2010;70:8948-58 pubmed publisher
Xu T, Xu Y, Liao C, Lau R, Goldkorn A. Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo. Mol Cancer Ther. 2010;9:438-49 pubmed publisher
Nardella C, Carracedo A, Alimonti A, Hobbs R, Clohessy J, Chen Z, et al. Differential requirement of mTOR in postmitotic tissues and tumorigenesis. Sci Signal. 2009;2:ra2 pubmed publisher
Horwitz K, Dye W, Harrell J, Kabos P, Sartorius C. Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Proc Natl Acad Sci U S A. 2008;105:5774-9 pubmed publisher
Stepp M, Liu Y, Pal Ghosh S, Jurjus R, Tadvalkar G, Sekaran A, et al. Reduced migration, altered matrix and enhanced TGFbeta1 signaling are signatures of mouse keratinocytes lacking Sdc1. J Cell Sci. 2007;120:2851-63 pubmed
product information
Antigen :
CD49f
Apps. Abbrev. :
FC, IHC-P
Cat # :
313623
Clone :
GoH3
Item :
Brilliant Violet 421™ anti-human/mouse CD49f
Isotype :
Rat IgG2a, κ
Other Names :
VLA-6 α chain, α6 integrin, integrin α6, ITGA6
Size :
25 tests
Price (USD) :
198 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
BV421
Immunogen :
Mouse mammary tumor cells
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation^1,5, in vitro and in vivo blocking of cell binding to laminin and blocking the function of integrin a6^1,4, and immunohistochemistry of acetone-fixed frozen sections^2,3,5. The GoH3 antibody has been reported to block laminin binding in vitro and to block integrin a6 function in vivo.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA