product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human/mouse CD49f
catalog :
313615
quantity :
25 tests
price :
149 USD
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
GoH3
reactivity :
human, mouse, rhesus macaque
application :
flow cytometry
more info or order :
citations: 38
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200
Mevel R, Steiner I, Mason S, Galbraith L, Patel R, Fadlullah M, et al. RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development. elife. 2020;9: pubmed publisher
  • flow cytometry; human; loading ...; fig 4
Cichon M, Moruzzi M, Shqau T, Miller E, Mehner C, Ethier S, et al. MYC Is a Crucial Mediator of TGF?-Induced Invasion in Basal Breast Cancer. Cancer Res. 2016;76:3520-30 pubmed publisher
  • flow cytometry; mouse
Goldstein A, Huang J, Guo C, Garraway I, Witte O. Identification of a cell of origin for human prostate cancer. Science. 2010;329:568-71 pubmed publisher
Haensel D, Gaddam S, Li N, Gonzalez F, Patel T, Cloutier J, et al. LY6D marks pre-existing resistant basosquamous tumor subpopulations. Nat Commun. 2022;13:7520 pubmed publisher
Murrow L, Weber R, Caruso J, McGinnis C, Phong K, Gascard P, et al. Mapping hormone-regulated cell-cell interaction networks in the human breast at single-cell resolution. Cell Syst. 2022;13:644-664.e8 pubmed publisher
Yasuhara R, Kang S, Irie T, Mabuchi Y, Kujiraoka S, Yukimori A, et al. Role of Snai2 and Notch signaling in salivary gland myoepithelial cell fate. Lab Invest. 2022;: pubmed publisher
Liang D, Sun Q, Zhu Z, Wang C, Ye S, Li Z, et al. Xenotransplantation of Human Spermatogonia Into Various Mouse Recipient Models. Front Cell Dev Biol. 2022;10:883314 pubmed publisher
Werner R, Nekritz E, Yan K, Ju B, Shaner B, Easton J, et al. Single-cell analysis reveals the Comma-1D cell line as a unique model for mammary gland development and breast cancer. J Cell Sci. 2022;135: pubmed publisher
Berg A, Rowson Hodel A, Hu M, KEELING M, Wu H, VanderVorst K, et al. The Cationic Amphiphilic Drug Hexamethylene Amiloride Eradicates Bulk Breast Cancer Cells and Therapy-Resistant Subpopulations with Similar Efficiencies. Cancers (Basel). 2022;14: pubmed publisher
Siddharth S, Parida S, Muniraj N, Hercules S, Lim D, Nagalingam A, et al. Concomitant activation of GLI1 and Notch1 contributes to racial disparity of human triple negative breast cancer progression. elife. 2021;10: pubmed publisher
Nekritz E, Rodríguez Barrueco R, Yan K, Davis M, Werner R, Devis Jauregui L, et al. miR-424/503 modulates Wnt/β-catenin signaling in the mammary epithelium by targeting LRP6. EMBO Rep. 2021;22:e53201 pubmed publisher
Huang S, Kuri P, Aubert Y, Brewster M, Li N, Farrelly O, et al. Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization. Cell Stem Cell. 2021;28:1582-1596.e6 pubmed publisher
Valdes Mora F, Salomon R, Gloss B, Law A, Venhuizen J, Castillo L, et al. Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype. Cell Rep. 2021;35:108945 pubmed publisher
Wang C, Zhang M, Garcia G, Tian E, Cui Q, Chen X, et al. ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response. Cell Stem Cell. 2021;28:331-342.e5 pubmed publisher
Parida S, Wu S, Siddharth S, Wang G, Muniraj N, Nagalingam A, et al. A Procarcinogenic Colon Microbe Promotes Breast Tumorigenesis and Metastatic Progression and Concomitantly Activates Notch and β-Catenin Axes. Cancer Discov. 2021;11:1138-1157 pubmed publisher
Wang D, Hu X, Liu C, Jia Y, Bai Y, Cai C, et al. Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers. Cell Res. 2019;29:832-845 pubmed publisher
Han Y, Feng H, Sun J, Liang X, Wang Z, Xing W, et al. Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation. J Clin Invest. 2019;130: pubmed publisher
Haas T, Sciuto M, Brunetto L, Valvo C, Signore M, Fiori M, et al. Integrin ?7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma. Cell Stem Cell. 2017;21:35-50.e9 pubmed publisher
Dall G, Vieusseux J, Korach K, Arao Y, Hewitt S, Hamilton K, et al. SCA-1 Labels a Subset of Estrogen-Responsive Bipotential Repopulating Cells within the CD24+ CD49fhi Mammary Stem Cell-Enriched Compartment. Stem Cell Reports. 2017;8:417-431 pubmed publisher
Cai S, Kalisky T, Sahoo D, Dalerba P, Feng W, Lin Y, et al. A Quiescent Bcl11b High Stem Cell Population Is Required for Maintenance of the Mammary Gland. Cell Stem Cell. 2017;20:247-260.e5 pubmed publisher
Skowron K, Pitroda S, Namm J, Balogun O, Beckett M, Zenner M, et al. Basal Tumor Cell Isolation and Patient-Derived Xenograft Engraftment Identify High-Risk Clinical Bladder Cancers. Sci Rep. 2016;6:35854 pubmed publisher
Liu S, Cadaneanu R, Zhang B, Huo L, Lai K, Li X, et al. Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone. PLoS ONE. 2016;11:e0163232 pubmed publisher
Li Y, Hong N, Zhang A, Chen W, Wang R, Xu X, et al. Enhancing mammary differentiation by overcoming lineage-specific epigenetic modification and signature gene expression of fibroblast-derived iPSCs. Cell Death Dis. 2014;5:e1550 pubmed publisher
Saenz F, Ory V, Alotaiby M, Rosenfield S, Furlong M, Cavalli L, et al. Conditionally reprogrammed normal and transformed mouse mammary epithelial cells display a progenitor-cell-like phenotype. PLoS ONE. 2014;9:e97666 pubmed publisher
Chang J, Wang C, Liu J, Huang Y, Jin C, Yang C, et al. Fibroblast growth factor signaling is essential for self-renewal of dental epithelial stem cells. J Biol Chem. 2013;288:28952-61 pubmed publisher
Chang J, Wang C, Jin C, Yang C, Huang Y, Liu J, et al. Self-renewal and multilineage differentiation of mouse dental epithelial stem cells. Stem Cell Res. 2013;11:990-1002 pubmed publisher
Szade K, Bukowska Strakova K, Nowak W, Szade A, Kachamakova Trojanowska N, Zukowska M, et al. Murine bone marrow Lin?Sca?1?CD45? very small embryonic-like (VSEL) cells are heterogeneous population lacking Oct-4A expression. PLoS ONE. 2013;8:e63329 pubmed publisher
Van Saen D, Goossens E, Aerts J, Haentjens P, Tournaye H. Does early cell death cause germ cell loss after intratesticular tissue grafting?. Fertil Steril. 2013;99:1264-1272.e1 pubmed publisher
Oeztuerk Winder F, Guinot A, Ochalek A, Ventura J. Regulation of human lung alveolar multipotent cells by a novel p38α MAPK/miR-17-92 axis. EMBO J. 2012;31:3431-41 pubmed publisher
Volkmer J, Sahoo D, Chin R, Ho P, Tang C, Kurtova A, et al. Three differentiation states risk-stratify bladder cancer into distinct subtypes. Proc Natl Acad Sci U S A. 2012;109:2078-83 pubmed publisher
Lai K, Yamashita S, Vitkus S, Shyr C, Yeh S, Chang C. Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptor. Mol Endocrinol. 2012;26:52-66 pubmed publisher
Grange C, Tapparo M, Collino F, Vitillo L, Damasco C, Deregibus M, et al. Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Cancer Res. 2011;71:5346-56 pubmed publisher
Jo M, Eastman B, Webb D, Stoletov K, Klemke R, Gonias S. Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Cancer Res. 2010;70:8948-58 pubmed publisher
Xu T, Xu Y, Liao C, Lau R, Goldkorn A. Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo. Mol Cancer Ther. 2010;9:438-49 pubmed publisher
Morimoto H, Kanatsu Shinohara M, Takashima S, Chuma S, Nakatsuji N, Takehashi M, et al. Phenotypic plasticity of mouse spermatogonial stem cells. PLoS ONE. 2009;4:e7909 pubmed publisher
Nardella C, Carracedo A, Alimonti A, Hobbs R, Clohessy J, Chen Z, et al. Differential requirement of mTOR in postmitotic tissues and tumorigenesis. Sci Signal. 2009;2:ra2 pubmed publisher
Horwitz K, Dye W, Harrell J, Kabos P, Sartorius C. Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Proc Natl Acad Sci U S A. 2008;105:5774-9 pubmed publisher
Stepp M, Liu Y, Pal Ghosh S, Jurjus R, Tadvalkar G, Sekaran A, et al. Reduced migration, altered matrix and enhanced TGFbeta1 signaling are signatures of mouse keratinocytes lacking Sdc1. J Cell Sci. 2007;120:2851-63 pubmed
product information
Antigen :
CD49f
Apps. Abbrev. :
FC
Cat # :
313615
Clone :
GoH3
Item :
APC anti-human/mouse CD49f
Isotype :
Rat IgG2a, κ
Other Names :
VLA-6 α chain, α6 integrin, integrin α6, ITGA6
Size :
25 tests
Price (USD) :
149 USD
Reactivity :
Human, Mouse, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC
Immunogen :
Mouse mammary tumor cells
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation^1,5, in vitro and in vivo blocking of cell binding to laminin and blocking the function of integrin a6^1,4, and immunohistochemistry of acetone-fixed frozen sections^2,3,5. The GoH3 antibody has been reported to block laminin binding in vitro and to block integrin a6 function in vivo.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA