LEAF™ Purified anti-human/mouse CD49f | BioLegend 313614 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

LEAF™ Purified anti-human/mouse CD49f

catalog :

313614

quantity :

200 ug

price :

250 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

GoH3

reactivity :

human, mouse, dogs, bovine, chimpanzee, rhesus macaque

application :

immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, mass cytometry

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:20; loading ...; fig 2d	Katsuda T, Matsuzaki J, Yamaguchi T, Yamada Y, Prieto Vila M, Hosaka K, et al. Generation of human hepatic progenitor cells with regenerative and metabolic capacities from primary hepatocytes. elife. 2019;8: pubmed publisher
mass cytometry; human; loading ...; fig 3a	Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed publisher
flow cytometry; human; loading ...; fig 9b flow cytometry; mouse; loading ...; fig 2a	Casey A, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, et al. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. J Cell Biol. 2018;217:2951-2974 pubmed publisher
flow cytometry; mouse; fig 2a	Yokota Nakatsuma A, Ohoka Y, Takeuchi H, Song S, Iwata M. Beta 1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties. Sci Rep. 2016;6:37914 pubmed publisher
flow cytometry; mouse; loading ...; fig 1a	Quantius J, Schmoldt C, Vazquez Armendariz A, Becker C, El Agha E, Wilhelm J, et al. Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair. PLoS Pathog. 2016;12:e1005544 pubmed publisher
flow cytometry; human; fig 1	Hines W, Yaswen P, Bissell M. Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias. Nat Commun. 2015;6:6927 pubmed publisher
flow cytometry; mouse	Goldstein A, Huang J, Guo C, Garraway I, Witte O. Identification of a cell of origin for human prostate cancer. Science. 2010;329:568-71 pubmed publisher
	Oeztuerk Winder F, Guinot A, Ochalek A, Ventura J. Regulation of human lung alveolar multipotent cells by a novel p38Î± MAPK/miR-17-92 axis. EMBO J. 2012;31:3431-41 pubmed publisher
	Lai K, Yamashita S, Vitkus S, Shyr C, Yeh S, Chang C. Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptor. Mol Endocrinol. 2012;26:52-66 pubmed publisher
	Grange C, Tapparo M, Collino F, Vitillo L, Damasco C, Deregibus M, et al. Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Cancer Res. 2011;71:5346-56 pubmed publisher
	Jo M, Eastman B, Webb D, Stoletov K, Klemke R, Gonias S. Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Cancer Res. 2010;70:8948-58 pubmed publisher
	Xu T, Xu Y, Liao C, Lau R, Goldkorn A. Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo. Mol Cancer Ther. 2010;9:438-49 pubmed publisher
	Nardella C, Carracedo A, Alimonti A, Hobbs R, Clohessy J, Chen Z, et al. Differential requirement of mTOR in postmitotic tissues and tumorigenesis. Sci Signal. 2009;2:ra2 pubmed publisher
	Horwitz K, Dye W, Harrell J, Kabos P, Sartorius C. Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Proc Natl Acad Sci U S A. 2008;105:5774-9 pubmed publisher
	Stepp M, Liu Y, Pal Ghosh S, Jurjus R, Tadvalkar G, Sekaran A, et al. Reduced migration, altered matrix and enhanced TGFbeta1 signaling are signatures of mouse keratinocytes lacking Sdc1. J Cell Sci. 2007;120:2851-63 pubmed

product information

Antigen :

CD49f

Apps. Abbrev. :

Flow Cytometry, ICC, IHC-F, IP, Block

Cat # :

313614

Clone :

GoH3

Item :

LEAF™ Purified anti-human/mouse CD49f

Isotype :

Rat IgG2a, kappa

Other Names :

VLA-6 alpha chain, alpha6 integrin, integrin alpha6, ITGA6

Size :

200 ug

Price (USD) :

250 USD

Reactivity :

Human, African Green, Mouse, Baboon, Capuchin Monkey, Cat (Feline), Cattle (Bovine, Cow), Chimpanzee, Cynomolgus, Dog (Canine), Horse (Equine), Rabbit (Lapine), Rhesus, Sheep (Ovine), Swine (Pig, Porcine)

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

LEAF

Immunogen :

Mouse mammary tumor cells

Application Notes :

. Additional reported applications (for the relevant formats) include: immunoprecipitation 1,5 , in vitro and in vivo blocking of cell binding to laminin and blocking the function of integrin alpha 6 1,4 , and immunohistochemistry of acetone-fixed frozen sections 2,3,5 . The GoH3 antibody has been reported to block laminin binding in vitro and to block integrin alpha 6 function in vivo .