product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 488 anti-human/mouse CD49f
catalog :
313607
quantity :
25 tests
price :
124 USD
clonality :
monoclonal
host :
rat
conjugate :
AF488
clone name :
GoH3
reactivity :
human, mouse, rhesus macaque
application :
flow cytometry
more info or order :
citations: 34
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200
Mevel R, Steiner I, Mason S, Galbraith L, Patel R, Fadlullah M, et al. RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; 1:2000; loading ...; fig s1-1a
Tremblay M, Viala S, Shafer M, Graham Paquin A, Liu C, Bouchard M. Regulation of stem/progenitor cell maintenance by BMP5 in prostate homeostasis and cancer initiation. elife. 2020;9: pubmed publisher
  • flow cytometry; human; 1:20; loading ...; fig 2d
Katsuda T, Matsuzaki J, Yamaguchi T, Yamada Y, Prieto Vila M, Hosaka K, et al. Generation of human hepatic progenitor cells with regenerative and metabolic capacities from primary hepatocytes. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
  • flow cytometry; human; loading ...; fig 9b
Casey A, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, et al. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. J Cell Biol. 2018;217:2951-2974 pubmed publisher
  • flow cytometry; mouse; fig 2a
Yokota Nakatsuma A, Ohoka Y, Takeuchi H, Song S, Iwata M. Beta 1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties. Sci Rep. 2016;6:37914 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Quantius J, Schmoldt C, Vazquez Armendariz A, Becker C, El Agha E, Wilhelm J, et al. Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair. PLoS Pathog. 2016;12:e1005544 pubmed publisher
  • flow cytometry; mouse
Goldstein A, Huang J, Guo C, Garraway I, Witte O. Identification of a cell of origin for human prostate cancer. Science. 2010;329:568-71 pubmed publisher
Kaltenbach L, Martzloff P, Bambach S, Aizarani N, Mihlan M, Gavrilov A, et al. Slow integrin-dependent migration organizes networks of tissue-resident mast cells. Nat Immunol. 2023;24:915-924 pubmed publisher
Huber M, Casares Arias J, F xe4 ssler R, M xfc ller D, Strohmeyer N. In mitosis integrins reduce adhesion to extracellular matrix and strengthen adhesion to adjacent cells. Nat Commun. 2023;14:2143 pubmed publisher
Pandolfi E, Hsu F, Duhon M, Zheng Y, Goldsmith S, Fu J, et al. In vitro germ cell induction from fertile and infertile monozygotic twin research participants. Cell Rep Med. 2022;3:100782 pubmed publisher
Paterson N, Lämmermann T. Macrophage network dynamics depend on haptokinesis for optimal local surveillance. elife. 2022;11: pubmed publisher
Vaidyanathan S, Baik R, Chen L, Bravo D, Suarez C, Abazari S, et al. Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus. Mol Ther. 2022;30:223-237 pubmed publisher
Hancock G, Liu W, Peretz L, Chen D, Gell J, Collier A, et al. Divergent roles for KLF4 and TFCP2L1 in naive ground state pluripotency and human primordial germ cell development. Stem Cell Res. 2021;55:102493 pubmed publisher
Wang J, Zhang Y, Gao Y, Shan S, Li Q. EZH2 Regulates the Correlation between Skin Regeneration and the Duration of Mechanical Stretch. J Invest Dermatol. 2021;141:894-902.e9 pubmed publisher
Hertzano R, Gwilliam K, Rose K, Milon B, MATERN M. Cell Type-Specific Expression Analysis of the Inner Ear: A Technical Report. Laryngoscope. 2021;131 Suppl 5:S1-S16 pubmed publisher
Morris E, Gillespie J, Maxwell C, Dedhar S. A Model of Differential Mammary Growth Initiation by Stat3 and Asymmetric Integrin-α6 Inheritance. Cell Rep. 2020;30:3605-3615.e5 pubmed publisher
Kawai S, Yamazaki M, Shibuya K, Yamazaki M, Fujii E, Nakano K, et al. Three-dimensional culture models mimic colon cancer heterogeneity induced by different microenvironments. Sci Rep. 2020;10:3156 pubmed publisher
Chen D, Sun N, Hou L, Kim R, Faith J, Aslanyan M, et al. Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors. Cell Rep. 2019;29:4568-4582.e5 pubmed publisher
Vaidyanathan S, Salahudeen A, Sellers Z, Bravo D, Choi S, Batish A, et al. High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia. Cell Stem Cell. 2020;26:161-171.e4 pubmed publisher
Lepletier A, Hun M, Hammett M, Wong K, Naeem H, Hedger M, et al. Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging. Cell Rep. 2019;27:3887-3901.e4 pubmed publisher
Luchsinger L, Strikoudis A, Danzl N, Bush E, Finlayson M, Satwani P, et al. Harnessing Hematopoietic Stem Cell Low Intracellular Calcium Improves Their Maintenance In Vitro. Cell Stem Cell. 2019;: pubmed publisher
Chen D, Liu W, Zimmerman J, Pastor W, Kim R, Hosohama L, et al. The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation. Cell Rep. 2018;25:3591-3602.e5 pubmed publisher
Peuhu E, Salomaa S, De Franceschi N, Potter C, Sundberg J, Pouwels J. Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice. PLoS ONE. 2017;12:e0186628 pubmed publisher
Park H, Park J, Lee H, Kim S, Yun J, Kim M, et al. Integrins functioning in uterine endometrial stromal and epithelial cells in estrus. Reproduction. 2017;153:351-360 pubmed publisher
Davis F, Janoshazi A, Janardhan K, Steinckwich N, D Agostin D, Petranka J, et al. Essential role of Orai1 store-operated calcium channels in lactation. Proc Natl Acad Sci U S A. 2015;112:5827-32 pubmed publisher
Oeztuerk Winder F, Guinot A, Ochalek A, Ventura J. Regulation of human lung alveolar multipotent cells by a novel p38α MAPK/miR-17-92 axis. EMBO J. 2012;31:3431-41 pubmed publisher
Riboldi M, Rubio C, Pellicer A, Gil Salom M, Simon C. In vitro production of haploid cells after coculture of CD49f+ with Sertoli cells from testicular sperm extraction in nonobstructive azoospermic patients. Fertil Steril. 2012;98:580-590.e4 pubmed publisher
Lai K, Yamashita S, Vitkus S, Shyr C, Yeh S, Chang C. Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptor. Mol Endocrinol. 2012;26:52-66 pubmed publisher
Grange C, Tapparo M, Collino F, Vitillo L, Damasco C, Deregibus M, et al. Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Cancer Res. 2011;71:5346-56 pubmed publisher
Jo M, Eastman B, Webb D, Stoletov K, Klemke R, Gonias S. Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Cancer Res. 2010;70:8948-58 pubmed publisher
Xu T, Xu Y, Liao C, Lau R, Goldkorn A. Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo. Mol Cancer Ther. 2010;9:438-49 pubmed publisher
Nardella C, Carracedo A, Alimonti A, Hobbs R, Clohessy J, Chen Z, et al. Differential requirement of mTOR in postmitotic tissues and tumorigenesis. Sci Signal. 2009;2:ra2 pubmed publisher
Horwitz K, Dye W, Harrell J, Kabos P, Sartorius C. Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Proc Natl Acad Sci U S A. 2008;105:5774-9 pubmed publisher
Stepp M, Liu Y, Pal Ghosh S, Jurjus R, Tadvalkar G, Sekaran A, et al. Reduced migration, altered matrix and enhanced TGFbeta1 signaling are signatures of mouse keratinocytes lacking Sdc1. J Cell Sci. 2007;120:2851-63 pubmed
product information
Antigen :
CD49f
Apps. Abbrev. :
FC
Cat # :
313607
Clone :
GoH3
Item :
Alexa Fluor® 488 anti-human/mouse CD49f
Isotype :
Rat IgG2a, κ
Other Names :
VLA-6 α chain, α6 integrin, integrin α6, ITGA6
Size :
25 tests
Price (USD) :
124 USD
Reactivity :
Human, Mouse, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
A488
Immunogen :
Mouse mammary tumor cells
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation^1,5, in vitro and in vivo blocking of cell binding to laminin and blocking the function of integrin a6^1,4, and immunohistochemistry of acetone-fixed frozen sections^2,3,5. The GoH3 antibody has been reported to block laminin binding in vitro and to block integrin a6 function in vivo.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA