Brilliant Violet 785™ anti-human/mouse/rat CD278 (ICOS) | BioLegend 313533 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 785™ anti-human/mouse/rat CD278 (ICOS)

catalog :

313533

quantity :

25 tests

price :

171 USD

clonality :

monoclonal

host :

hamsters

conjugate :

Brilliant Violet 785

clone name :

C398.4A

reactivity :

human, mouse, rat

application :

flow cytometry, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 2b flow cytometry; human	Kinosada H, Yasunaga J, Shimura K, Miyazato P, Onishi C, Iyoda T, et al. HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors. PLoS Pathog. 2017;13:e1006120 pubmed publisher
flow cytometry; mouse; loading ...	Ramirez Carrozzi V, Sambandam A, Zhou M, Yan D, Kang J, Wu X, et al. Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone. J Allergy Clin Immunol. 2017;139:705-708.e6 pubmed publisher
flow cytometry; human; loading ...; fig 3	Zwang N, Zhang R, Germana S, Fan M, Hastings W, Cao A, et al. Selective Sparing of Human Tregs by Pharmacologic Inhibitors of the Phosphatidylinositol 3-Kinase and MEK Pathways. Am J Transplant. 2016;16:2624-38 pubmed publisher
blocking or activating experiments; mouse; 20 ug/ml; fig 7	Nelson M, Kundimi S, Bowers J, Rogers C, Huff L, Schwartz K, et al. The inducible costimulator augments Tc17 cell responses to self and tumor tissue. J Immunol. 2015;194:1737-47 pubmed publisher
flow cytometry; rat; fig 3	Xie L, Choudhury G, Winters A, Yang S, Jin K. Cerebral regulatory TÂ cells restrain microglia/macrophage-mediated inflammatory responses via IL-10. Eur J Immunol. 2015;45:180-91 pubmed publisher
	Bajana S, Pankow A, Liu K, Michniowska M, Urban J, Chen W, et al. Correlation between circulating innate lymphoid cell precursors and thymic function. iScience. 2022;25:103732 pubmed publisher
	Marangoni F, Zhakyp A, Corsini M, Geels S, Carrizosa E, Thelen M, et al. Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop. Cell. 2021;184:3998-4015.e19 pubmed publisher
	Field C, Baixauli F, Kyle R, Puleston D, Cameron A, Sanin D, et al. Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function. Cell Metab. 2020;31:422-437.e5 pubmed publisher
	Cai B, Dongiovanni P, Corey K, Wang X, Shmarakov I, Zheng Z, et al. Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis. Cell Metab. 2020;31:406-421.e7 pubmed publisher
	Ligorio M, Sil S, Malagon Lopez J, Nieman L, Misale S, Di Pilato M, et al. Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer. Cell. 2019;: pubmed publisher

product information

Antigen :

CD278

Apps. Abbrev. :

Cat # :

313533

Clone :

C398.4A

Item :

Brilliant Violet 785™ anti-human/mouse/rat CD278 (ICOS)

Isotype :

Armenian Hamster IgG

Other Names :

Inducible COStimulatory molecule, H4

Size :

25 tests

Price (USD) :

171 USD

Reactivity :

Human, Mouse, Rat

Clonality :

Monoclonal

Host :

Armenian Hamster

Conjugate/Tag/Label :

BV785

Immunogen :

Mouse T cell clone D10.G4.1

Application Notes :

The C398.4A antibody is useful for flow cytometric analysis and is able to costimulate T cell activation and proliferation. Additional reported applications (for the relevant formats) include: immunoprecipitation^1, in vitro costimulation of T cell activation^1,3,4, and spatial biology (IBEX)^5,6. The LEAF™ purified antibody (Endotoxin < 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 313512).;

more info or order :

BioLegend product webpage