Pacific Blue™ anti-human/mouse/rat CD278 (ICOS) | BioLegend 313522 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Pacific Blue™ anti-human/mouse/rat CD278 (ICOS)

catalog :

313522

quantity :

100 μg

price :

300 USD

clonality :

monoclonal

host :

hamsters

conjugate :

Pacific Blue

clone name :

C398.4A

reactivity :

African green monkey, human, mouse, rat

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig s1a	Mantani P, Dunér P, Ljungcrantz I, Nilsson J, Bjorkbacka H, Fredrikson G. ILC2 transfers to apolipoprotein E deficient mice reduce the lipid content of atherosclerotic lesions. BMC Immunol. 2019;20:47 pubmed publisher
flow cytometry; African green monkey; fig 1	Vargas Inchaustegui D, Demers A, Shaw J, Kang G, Ball D, Tuero I, et al. Vaccine Induction of Lymph Node-Resident Simian Immunodeficiency Virus Env-Specific T Follicular Helper Cells in Rhesus Macaques. J Immunol. 2016;196:1700-10 pubmed publisher
flow cytometry; mouse	Kawamoto S, Tran T, Maruya M, Suzuki K, Doi Y, Tsutsui Y, et al. The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut. Science. 2012;336:485-9 pubmed publisher
	Aguilar Briseño J, Upasani V, Ellen B, Moser J, Pauzuolis M, Ruiz Silva M, et al. TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis. Nat Commun. 2020;11:3177 pubmed publisher
	Cassotta A, Mikol V, Bertrand T, Pouzieux S, Le Parc J, Ferrari P, et al. A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients. Nat Med. 2019;25:1402-1407 pubmed publisher
	Sparber F, De Gregorio C, Steckholzer S, Ferreira F, Dolowschiak T, Ruchti F, et al. The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation. Cell Host Microbe. 2019;25:389-403.e6 pubmed publisher
	Amodio D, Cotugno N, Macchiarulo G, Rocca S, Dimopoulos Y, Castrucci M, et al. Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza Vaccination. J Immunol. 2018;200:538-550 pubmed publisher
	Westernberg L, Schulten V, Greenbaum J, Natali S, Tripple V, McKinney D, et al. T-cell epitope conservation across allergen species is a major determinant of immunogenicity. J Allergy Clin Immunol. 2016;138:571-578.e7 pubmed publisher
	Blackburn M, Zhong Min M, Caccuri F, McKinnon K, Schifanella L, Guan Y, et al. Regulatory and Helper Follicular T Cells and Antibody Avidity to Simian Immunodeficiency Virus Glycoprotein 120. J Immunol. 2015;195:3227-36 pubmed publisher
	Yamamoto T, Lynch R, Gautam R, Matus Nicodemos R, Schmidt S, Boswell K, et al. Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection. Sci Transl Med. 2015;7:298ra120 pubmed publisher
	Hong J, Amancha P, Rogers K, Courtney C, Havenar Daughton C, Crotty S, et al. Early lymphoid responses and germinal center formation correlate with lower viral load set points and better prognosis of simian immunodeficiency virus infection. J Immunol. 2014;193:797-806 pubmed publisher
	DeFuria J, Belkina A, Jagannathan Bogdan M, Snyder Cappione J, Carr J, Nersesova Y, et al. B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile. Proc Natl Acad Sci U S A. 2013;110:5133-8 pubmed publisher

product information

Antigen :

CD278

Apps. Abbrev. :

Cat # :

313522

Clone :

C398.4A

Item :

Pacific Blue™ anti-human/mouse/rat CD278 (ICOS)

Isotype :

Armenian Hamster IgG

Other Names :

Inducible COStimulatory molecule, H4

Size :

100 μg

Price (USD) :

300 USD

Reactivity :

Human, Mouse, Rat

Clonality :

Monoclonal

Host :

Armenian Hamster

Conjugate/Tag/Label :

Immunogen :

Mouse T cell clone D10.G4.1

Application Notes :

The C398.4A antibody is useful for flow cytometric analysis and is able to costimulate T cell activation and proliferation. Additional reported applications (for the relevant formats) include: immunoprecipitation^1, in vitro costimulation of T cell activation^1,3,4, and spatial biology (IBEX)^5,6. The LEAF™ purified antibody (Endotoxin < 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 313512).;

more info or order :

BioLegend product webpage