FITC anti-human/mouse/rat CD278 (ICOS) | BioLegend 313506 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

FITC anti-human/mouse/rat CD278 (ICOS)

catalog :

313506

quantity :

100 μg

price :

165 USD

clonality :

monoclonal

host :

hamsters

conjugate :

FITC

clone name :

C398.4A

reactivity :

human, mouse, rat

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse	Kawamoto S, Tran T, Maruya M, Suzuki K, Doi Y, Tsutsui Y, et al. The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut. Science. 2012;336:485-9 pubmed publisher
	Shiozawa S, Tsumiyama K, Miyazaki Y, Uto K, Sakurai K, Nakashima T, et al. DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus. iScience. 2022;25:103537 pubmed publisher
	Beziat V, Rapaport F, Hu J, Titeux M, Bonnet des Claustres M, Bourgey M, et al. Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy. Cell. 2021;184:3812-3828.e30 pubmed publisher
	O Connor M, Muir R, Chakhtoura M, Fang M, Moysi E, Moir S, et al. A follicular regulatory Innate Lymphoid Cell population impairs interactions between germinal center Tfh and B cells. Commun Biol. 2021;4:563 pubmed publisher
	Trefzer A, Kadam P, Wang S, Pennavaria S, Lober B, Akçabozan B, et al. Dynamic adoption of anergy by antigen-exhausted CD4+ T cells. Cell Rep. 2021;34:108748 pubmed publisher
	Elsner R, Shlomchik M. IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression. Cell Rep. 2019;29:2796-2809.e5 pubmed publisher
	Kim C, Lee C, Jung J, Ghosh A, Hasan S, Hwang S, et al. The Transcription Factor Ets1 Suppresses T Follicular Helper Type 2 Cell Differentiation to Halt the Onset of Systemic Lupus Erythematosus. Immunity. 2018;49:1034-1048.e8 pubmed publisher
	Bolton D, McGinnis K, Finak G, Chattopadhyay P, Gottardo R, Roederer M. Combined single-cell quantitation of host and SIV genes and proteins ex vivo reveals host-pathogen interactions in individual cells. PLoS Pathog. 2017;13:e1006445 pubmed publisher
	Colineau L, Rouers A, Yamamoto T, Xu Y, Urrutia A, Pham H, et al. HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation. PLoS ONE. 2015;10:e0140978 pubmed publisher
	Tonti E, Fedeli M, Napolitano A, Iannacone M, von Andrian U, Guidotti L, et al. Follicular helper NKT cells induce limited B cell responses and germinal center formation in the absence of CD4(+) T cell help. J Immunol. 2012;188:3217-22 pubmed publisher
	Rankin A, MacLeod H, Keegan S, Andreyeva T, Lowe L, Bloom L, et al. IL-21 receptor is critical for the development of memory B cell responses. J Immunol. 2011;186:667-74 pubmed publisher

product information

Antigen :

CD278

Apps. Abbrev. :

Cat # :

313506

Clone :

C398.4A

Item :

FITC anti-human/mouse/rat CD278 (ICOS)

Isotype :

Armenian Hamster IgG

Other Names :

Inducible COStimulatory molecule, H4

Size :

100 μg

Price (USD) :

165 USD

Reactivity :

Human, Mouse, Rat

Clonality :

Monoclonal

Host :

Armenian Hamster

Conjugate/Tag/Label :

FITC

Immunogen :

Mouse T cell clone D10.G4.1

Application Notes :

The C398.4A antibody is useful for flow cytometric analysis and is able to costimulate T cell activation and proliferation. Additional reported applications (for the relevant formats) include: immunoprecipitation^1, in vitro costimulation of T cell activation^1,3,4, and spatial biology (IBEX)^5,6. The LEAF™ purified antibody (Endotoxin < 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 313512).;

more info or order :

BioLegend product webpage