product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human/mouse ZAP-70
catalog :
313402
quantity :
100 μg
price :
183 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1E7.2
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1a
Pugh J, Nemat Gorgani N, Norman P, Guethlein L, Parham P. Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage. J Immunol. 2018;200:1146-1158 pubmed publisher
  • western blot; mouse; fig s1
Muro R, Nitta T, Nakano K, Okamura T, Takayanagi H, Suzuki H. γδTCR recruits the Syk/PI3K axis to drive proinflammatory differentiation program. J Clin Invest. 2018;128:415-426 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
González Pérez G, Lamousé Smith E. Gastrointestinal Microbiome Dysbiosis in Infant Mice Alters Peripheral CD8+ T Cell Receptor Signaling. Front Immunol. 2017;8:265 pubmed publisher
Bennstein S, Weinhold S, Manser A, Scherenschlich N, Noll A, Raba K, et al. Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells. elife. 2020;9: pubmed publisher
Xu X, Hou B, Fulzele A, Masubuchi T, Zhao Y, Wu Z, et al. PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2. J Cell Biol. 2020;219: pubmed publisher
Tai T, Pai S, Ho I. GATA-3 regulates the homeostasis and activation of CD8+ T cells. J Immunol. 2013;190:428-37 pubmed publisher
Jamroziak K, Szemraj Z, Grzybowska Izydorczyk O, Szemraj J, Bieniasz M, Cebula B, et al. CD38 gene polymorphisms contribute to genetic susceptibility to B-cell chronic lymphocytic leukemia: evidence from two case-control studies in Polish Caucasians. Cancer Epidemiol Biomarkers Prev. 2009;18:945-53 pubmed publisher
product information
Antigen :
ZAP-70
Apps. Abbrev. :
ICFC, WB, IP
Cat # :
313402
Clone :
1E7.2
Item :
Purified anti-human/mouse ZAP-70
Isotype :
Mouse IgG1, κ
Other Names :
Zeta chain associated protein kinase, SYK related tyrosine kinase
Size :
100 μg
Price (USD) :
183 USD
Reactivity :
Human, Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
GST-fusion protein corresponding to residues 282-307 of human ZAP-70
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation^2, Western blotting^2.This product is for in vitro research use only. It is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic, therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes, contact The Regents of the University of California.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA