product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-human CD117 (c-kit)
catalog :
313211
quantity :
25 tests
price :
112 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE/Cy7
clone name :
104D2
reactivity :
human
application :
flow cytometry
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2c
Bai H, Liu Y, Xie Y, Hoyle D, Brodsky R, Cheng L, et al. Definitive Hematopoietic Multipotent Progenitor Cells Are Transiently Generated From Hemogenic Endothelial Cells in Human Pluripotent Stem Cells. J Cell Physiol. 2016;231:1065-76 pubmed publisher
  • flow cytometry; human; fig 1
Hines W, Yaswen P, Bissell M. Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias. Nat Commun. 2015;6:6927 pubmed publisher
  • flow cytometry; human
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
Skovdahl H, Gopalakrishnan S, Svendsen T, Granlund A, Bakke I, Ginbot Z, et al. Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration. Front Pharmacol. 2021;12:679741 pubmed publisher
Thomas A, Takahashi N, Rajapakse V, Zhang X, Sun Y, Ceribelli M, et al. Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress. Cancer Cell. 2021;39:566-579.e7 pubmed publisher
Yi W, Zhang Y, Liu B, Zhou Y, Liao D, Qiao X, et al. Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration. Cell Rep. 2021;34:108922 pubmed publisher
Kerr B, Shi L, Jinnah A, Harris K, Willey J, Lennon D, et al. Kindlin-3 mutation in mesenchymal stem cells results in enhanced chondrogenesis. Exp Cell Res. 2021;399:112456 pubmed publisher
Penkava F, Velasco Herrera M, Young M, Yager N, Nwosu L, Pratt A, et al. Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis. Nat Commun. 2020;11:4767 pubmed publisher
Fang F, Li Z, Zhao Q, Ye Z, Gu X, Pan F, et al. Induced Pluripotent Stem Cells Derived From Two Idiopathic Azoospermia Patients Display Compromised Differentiation Potential for Primordial Germ Cell Fate. Front Cell Dev Biol. 2020;8:432 pubmed publisher
Liao Y, Ivanova L, Sivalenka R, Plumer T, Zhu H, Zhang X, et al. Efficacy of Human Placental-Derived Stem Cells in Collagen VII Knockout (Recessive Dystrophic Epidermolysis Bullosa) Animal Model. Stem Cells Transl Med. 2018;7:530-542 pubmed publisher
Allan J, Roboz G, Askin G, Ritchie E, SCANDURA J, Christos P, et al. CD25 expression and outcomes in older patients with acute myelogenous leukemia treated with plerixafor and decitabine. Leuk Lymphoma. 2018;59:821-828 pubmed publisher
Serr I, Fürst R, Achenbach P, Scherm M, Gökmen F, Haupt F, et al. Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice. Nat Commun. 2016;7:10991 pubmed publisher
De Grove K, Provoost S, Verhamme F, Bracke K, Joos G, Maes T, et al. Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung. PLoS ONE. 2016;11:e0145961 pubmed publisher
Ogaki S, Morooka M, Otera K, Kume S. A cost-effective system for differentiation of intestinal epithelium from human induced pluripotent stem cells. Sci Rep. 2015;5:17297 pubmed publisher
Le Gall M, Crépin R, Neiveyans M, Auclair C, Fan Y, Zhou Y, et al. Neutralization of KIT Oncogenic Signaling in Leukemia with Antibodies Targeting KIT Membrane Proximal Domain 5. Mol Cancer Ther. 2015;14:2595-605 pubmed publisher
Nagano M, Yamashita T, Hamada H, Ohneda K, Kimura K, Nakagawa T, et al. Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood. Blood. 2007;110:151-60 pubmed
product information
Antigen :
CD117
Apps. Abbrev. :
FC
Cat # :
313211
Clone :
104D2
Item :
PE/Cyanine7 anti-human CD117 (c-kit)
Isotype :
Mouse IgG1, κ
Other Names :
Stem cell factor receptor, c-kit, mast cell growth factor receptor, steel factor receptor
Size :
25 tests
Price (USD) :
112 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE_CYANINE7
Immunogen :
MOLM-1 megakaryocytic cell line
Application Notes :
The 104D2 antibody does not block binding of c-Kit ligand. Additional reported applications (for the relevant formats) include: immunoprecipitation^1, immunofluorescence microscopy^1, and spatial biology (IBEX)^4,5.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA