product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD117 (c-kit)
catalog :
313206
quantity :
100 tests
price :
288 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
104D2
reactivity :
human
application :
immunohistochemistry, flow cytometry
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:20; loading ...; fig ED7c
Britschgi A, Duss S, Kim S, Couto J, Brinkhaus H, Koren S, et al. The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα. Nature. 2017;541:541-545 pubmed publisher
  • flow cytometry; human
Denkovskij J, Rudys R, Bernotiene E, Minderis M, Bagdonas S, Kirdaite G. Cell surface markers and exogenously induced PpIX in synovial mesenchymal stem cells. Cytometry A. 2015;87:1001-11 pubmed publisher
  • flow cytometry; human
Fernandez L, Valentin J, Zalacain M, Leung W, Patino Garcia A, Perez Martinez A. Activated and expanded natural killer cells target osteosarcoma tumor initiating cells in an NKG2D-NKG2DL dependent manner. Cancer Lett. 2015;368:54-63 pubmed publisher
  • immunohistochemistry; human; tbl 4
Leung A, Murphy G. Multisystemic Disease Modeling of Liver-Derived Protein Folding Disorders Using Induced Pluripotent Stem Cells (iPSCs). Methods Mol Biol. 2016;1353:261-70 pubmed publisher
  • flow cytometry; human
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
Wheeler M, Stilp A, Rao S, Halld xf3 rsson B, Beyter D, Wen J, et al. Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program. Nat Commun. 2022;13:7592 pubmed publisher
Leibel S, Tseu I, Zhou A, Hodges A, Yin J, Bilodeau C, et al. Metabolomic profiling of human pluripotent stem cell differentiation into lung progenitors. iScience. 2022;25:103797 pubmed publisher
Shalabi S, Miyano M, Sayaman R, Lopez J, Jokela T, Todhunter M, et al. Evidence for accelerated aging in mammary epithelia of women carrying germline BRCA1 or BRCA2 mutations. Nat Aging. 2021;1:838-849 pubmed publisher
Imai Y, Kusakabe M, Nagai M, Yasuda K, Yamanishi K. Dupilumab Effects on Innate Lymphoid Cell and Helper T Cell Populations in Patients with Atopic Dermatitis. JID Innov. 2021;1:100003 pubmed publisher
Raman S, Buongervino S, Lane M, Zhelev D, Zhu Z, Cui H, et al. A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope. Cell Rep Med. 2021;2:100344 pubmed publisher
Keck S, Galati Fournier V, Kym U, Moesch M, Usemann J, Muller I, et al. Lack of Mucosal Cholinergic Innervation Is Associated With Increased Risk of Enterocolitis in Hirschsprung's Disease. Cell Mol Gastroenterol Hepatol. 2021;12:507-545 pubmed publisher
Rao S, Yao Y, Soares de Brito J, Yao Q, Shen A, Watkinson R, et al. Dissecting ELANE neutropenia pathogenicity by human HSC gene editing. Cell Stem Cell. 2021;: pubmed publisher
Qiu J, Nordling S, Vasavada H, Butcher E, Hirschi K. Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification. Cell Rep. 2020;33:108465 pubmed publisher
Zhan C, Chen J, Chen J, Zhang L, Liu Y, Du H, et al. CaMK4-dependent phosphorylation of Akt/mTOR underlies Th17 excessive activation in experimental autoimmune prostatitis. FASEB J. 2020;34:14006-14023 pubmed publisher
Bennstein S, Weinhold S, Manser A, Scherenschlich N, Noll A, Raba K, et al. Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells. elife. 2020;9: pubmed publisher
Ruan S, Zhang H, Tian X, Zhang Z, Huang H, Shi C, et al. PHD Finger Protein 19 Enhances the Resistance of Ovarian Cancer Cells to Compound Fuling Granule by Protecting Cell Growth, Invasion, Migration, and Stemness. Front Pharmacol. 2020;11:150 pubmed publisher
Engeroff P, Caviezel F, Mueller D, Thoms F, Bachmann M, Vogel M. CD23 provides a noninflammatory pathway for IgE-allergen complexes. J Allergy Clin Immunol. 2020;145:301-311.e4 pubmed publisher
He H, Yu B, Liu Z, Ye G, You W, Hong Y, et al. Vascular progenitor cell senescence in patients with Marfan syndrome. J Cell Mol Med. 2019;23:4139-4152 pubmed publisher
Zou T, Gao L, Zeng Y, Li Q, Li Y, Chen S, et al. Organoid-derived C-Kit+/SSEA4- human retinal progenitor cells promote a protective retinal microenvironment during transplantation in rodents. Nat Commun. 2019;10:1205 pubmed publisher
Lu B, Klingbeil O, Tarumoto Y, Somerville T, Huang Y, Wei Y, et al. A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence. Cancer Cell. 2018;34:970-981.e8 pubmed publisher
Frazier T, Lee S, Bowles A, Semon J, Bunnell B, Wu X, et al. Gender and age-related cell compositional differences in C57BL/6 murine adipose tissue stromal vascular fraction. Adipocyte. 2018;7:183-189 pubmed publisher
Ran L, Chen Y, Sher J, Wong E, Murphy D, Zhang J, et al. FOXF1 Defines the Core-Regulatory Circuitry in Gastrointestinal Stromal Tumor. Cancer Discov. 2018;8:234-251 pubmed publisher
GORDON E, Simpson L, Rios C, Ringel L, Lachowicz Scroggins M, Peters M, et al. Alternative splicing of interleukin-33 and type 2 inflammation in asthma. Proc Natl Acad Sci U S A. 2016;113:8765-70 pubmed publisher
Mandl M, Schmitz S, Weber C, Hristov M. Characterization of the CD14++CD16+ monocyte population in human bone marrow. PLoS ONE. 2014;9:e112140 pubmed publisher
Sputova K, Garbe J, Pelissier F, Chang E, Stampfer M, Labarge M. Aging phenotypes in cultured normal human mammary epithelial cells are correlated with decreased telomerase activity independent of telomere length. Genome Integr. 2013;4:4 pubmed publisher
Luni C, Zagallo M, Albania L, Piccoli M, Pozzobon M, De Coppi P, et al. Design of a stirred multiwell bioreactor for expansion of CD34+ umbilical cord blood cells in hypoxic conditions. Biotechnol Prog. 2011;27:1154-62 pubmed publisher
Nagano M, Yamashita T, Hamada H, Ohneda K, Kimura K, Nakagawa T, et al. Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood. Blood. 2007;110:151-60 pubmed
product information
Antigen :
CD117
Apps. Abbrev. :
FC
Cat # :
313206
Clone :
104D2
Item :
APC anti-human CD117 (c-kit)
Isotype :
Mouse IgG1, κ
Other Names :
Stem cell factor receptor, c-kit, mast cell growth factor receptor, steel factor receptor
Size :
100 tests
Price (USD) :
288 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
MOLM-1 megakaryocytic cell line
Application Notes :
The 104D2 antibody does not block binding of c-Kit ligand. Additional reported applications (for the relevant formats) include: immunoprecipitation^1, immunofluorescence microscopy^1, and spatial biology (IBEX)^4,5.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA