Ultra-LEAF™ Purified anti-human CD40 | BioLegend 313019 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Ultra-LEAF™ Purified anti-human CD40

catalog :

313019

quantity :

100 μg

price :

116 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HB14

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 3

Reference
Fesneau O, Samson K, Rosales W, Jones B, Moudgil T, Fox B, et al. IL-12 drives the expression of the inhibitory receptor NKG2A on human tumor-reactive CD8 T cells. Nat Commun. 2024;15:9988 pubmed publisher
Kwak K, Sohn H, George R, Torgbor C, Manzella Lapeira J, Brzostowski J, et al. B cell responses to membrane-presented antigens require the function of the mechanosensitive cation channel Piezo1. Sci Signal. 2023;16:eabq5096 pubmed publisher
Jhuang K, Hsu M, Chen Y, Chang J, Zouali M. DNA methylation trajectories during innate and adaptive immune responses of human B lymphocytes. Immunology. 2023;169:344-357 pubmed publisher

product information

Antigen :

CD40

Apps. Abbrev. :

FC, Costim

Cat # :

313019

Clone :

HB14

Item :

Ultra-LEAF™ Purified anti-human CD40

Isotype :

Mouse IgG1, κ

Other Names :

BP50, TNFRSF5

Size :

100 μg

Price (USD) :

116 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

ULEAF

Application Notes :

Additional reported applications (for the relevant formats) include: costimulation of B cell proliferation, partial inhibition of CD40 binding to CD40L, and prevention of B cell apoptosis.^1 Alone, or in combination with TLR ligands, clone HIB14 stimulates B cells to produce IL-10 and differentiates it into regulatory B10 (IL-10 producing B cells).^7 The Ultra-LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 313019 & 313020).;

more info or order :

BioLegend product webpage