PE anti-human CD40 | BioLegend 313006 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human CD40

catalog :

313006

quantity :

100 tests

price :

210 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

HB14

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 6

Reference
Zander R, Kasmani M, Chen Y, Topchyan P, Shen J, Zheng S, et al. Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection. Immunity. 2022;55:475-493.e5 pubmed publisher
Saito T, Shukla N, Sato Kaneko F, Sako Y, Hosoya T, Yao S, et al. Small Molecule Calcium Channel Activator Potentiates Adjuvant Activity. ACS Chem Biol. 2022;17:217-229 pubmed publisher
Akhtar M, Mishra M, Yadav V, Yadav M, Gujar R, Lal S, et al. Runx proteins mediate protective immunity against Leishmania donovani infection by promoting CD40 expression on dendritic cells. PLoS Pathog. 2020;16:e1009136 pubmed publisher
Liang Y, Yu B, Chen J, Wu H, Xu Y, Yang B, et al. Thymic stromal lymphopoietin epigenetically upregulates Fc receptor γ subunit-related receptors on antigen-presenting cells and induces TH2/TH17 polarization through dectin-2. J Allergy Clin Immunol. 2019;144:1025-1035.e7 pubmed publisher
Mitchell K, Barreyro L, Todorova T, Taylor S, Antony Debré I, Narayanagari S, et al. IL1RAP potentiates multiple oncogenic signaling pathways in AML. J Exp Med. 2018;215:1709-1727 pubmed publisher
Thiemann S, Man J, Chang M, Lee B, Baum L. Galectin-1 regulates tissue exit of specific dendritic cell populations. J Biol Chem. 2015;290:22662-77 pubmed publisher

product information

Antigen :

CD40

Apps. Abbrev. :

Cat # :

313006

Clone :

HB14

Item :

PE anti-human CD40

Isotype :

Mouse IgG1, κ

Other Names :

BP50, TNFRSF5

Size :

100 tests

Price (USD) :

210 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Application Notes :

Additional reported applications (for the relevant formats) include: costimulation of B cell proliferation, partial inhibition of CD40 binding to CD40L, and prevention of B cell apoptosis.^1 Alone, or in combination with TLR ligands, clone HIB14 stimulates B cells to produce IL-10 and differentiates it into regulatory B10 (IL-10 producing B cells).^7 The Ultra-LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 313019 & 313020).;

more info or order :

BioLegend product webpage