Purified anti-human CD40 | BioLegend 313002 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-human CD40

catalog :

313002

quantity :

100 μg

price :

101 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HB14

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1b	Trabanelli S, Lecciso M, Salvestrini V, Cavo M, OÄadlÃkovÃ¡ D, Lemoli R, et al. PGE2-induced IDO1 inhibits the capacity of fully mature DCs to elicit an in vitro antileukemic immune response. J Immunol Res. 2015;2015:253191 pubmed publisher
flow cytometry; human; loading ...; fig 2a	Svajger U, Obermajer N, Jeras M. IFN-?-rich environment programs dendritic cells toward silencing of cytotoxic immune responses. J Leukoc Biol. 2014;95:33-46 pubmed publisher
	Syrimi E, Fennell E, Richter A, Vrljicak P, Stark R, Ott S, et al. The immune landscape of SARS-CoV-2-associated Multisystem Inflammatory Syndrome in Children (MIS-C) from acute disease to recovery. iScience. 2021;24:103215 pubmed publisher
	Gonzalez Figueroa P, Roco J, Papa I, Núñez Villacís L, Stanley M, Linterman M, et al. Follicular regulatory T cells produce neuritin to regulate B cells. Cell. 2021;184:1775-1789.e19 pubmed publisher
	Kennedy Darling J, Bhate S, Hickey J, Black S, Barlow G, Vazquez G, et al. Highly multiplexed tissue imaging using repeated oligonucleotide exchange reaction. Eur J Immunol. 2021;51:1262-1277 pubmed publisher
	Leylek R, Alcántara Hernández M, Granja J, Chavez M, Perez K, Diaz O, et al. Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity. Cell Rep. 2020;32:108180 pubmed publisher
	Pissani F, Schulte B, Eller M, Schultz B, Ratto Kim S, Marovich M, et al. Modulation of Vaccine-Induced CD4 T Cell Functional Profiles by Changes in Components of HIV Vaccine Regimens in Humans. J Virol. 2018;92: pubmed publisher
	Iwata Y, Matsushita T, Horikawa M, DiLillo D, Yanaba K, Venturi G, et al. Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood. 2011;117:530-41 pubmed publisher
	Jayakumar A, Donovan M, Tripathi V, Ramalho Ortigao M, McDowell M. Leishmania major infection activates NF-kappaB and interferon regulatory factors 1 and 8 in human dendritic cells. Infect Immun. 2008;76:2138-48 pubmed publisher

product information

Antigen :

CD40

Apps. Abbrev. :

FC, Costim

Cat # :

313002

Clone :

HB14

Item :

Purified anti-human CD40

Isotype :

Mouse IgG1, κ

Other Names :

BP50, TNFRSF5

Size :

100 μg

Price (USD) :

101 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Application Notes :

Additional reported applications (for the relevant formats) include: costimulation of B cell proliferation, partial inhibition of CD40 binding to CD40L, and prevention of B cell apoptosis.^1 Alone, or in combination with TLR ligands, clone HIB14 stimulates B cells to produce IL-10 and differentiates it into regulatory B10 (IL-10 producing B cells).^7 The Ultra-LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 313019 & 313020).;

more info or order :

BioLegend product webpage