product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human CD180 (RP105)
catalog :
312902
quantity :
100 μg
price :
194 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MHR73-11
reactivity :
human, rhesus macaque
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 1
Eriksen A, Torgersen M, Holm K, Abrahamsen G, Spurkland A, Moskaug J, et al. Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy. Autophagy. 2015;11:460-71 pubmed publisher
Bennstein S, Weinhold S, Manser A, Scherenschlich N, Noll A, Raba K, et al. Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells. elife. 2020;9: pubmed publisher
Gilljam K, Holm K, Zahoor M, Centonze F, Farhan H, Blomhoff H. Differential Effects of Reactive Oxygen Species on IgG versus IgM Levels in TLR-Stimulated B Cells. J Immunol. 2020;204:2133-2142 pubmed publisher
Poznanski S, Nham T, Chew M, Lee A, Hammill J, Fan I, et al. Expanded CD56superbrightCD16+ NK Cells from Ovarian Cancer Patients Are Cytotoxic against Autologous Tumor in a Patient-Derived Xenograft Murine Model. Cancer Immunol Res. 2018;6:1174-1185 pubmed publisher
Kikuchi J, Kuroda Y, Koyama D, Osada N, Izumi T, Yasui H, et al. Myeloma Cells Are Activated in Bone Marrow Microenvironment by the CD180/MD-1 Complex, Which Senses Lipopolysaccharide. Cancer Res. 2018;78:1766-1778 pubmed publisher
Holm K, Syljuåsen R, Hasvold G, Alsøe L, Nilsen H, Ivanauskiene K, et al. TLR9 stimulation of B-cells induces transcription of p53 and prevents spontaneous and irradiation-induced cell death independent of DNA damage responses. Implications for Common variable immunodeficiency. PLoS ONE. 2017;12:e0185708 pubmed publisher
Indrevær R, Moskaug J, Paur I, Bøhn S, Jørgensen S, Blomhoff R, et al. IRF4 Is a Critical Gene in Retinoic Acid-Mediated Plasma Cell Formation and Is Deregulated in Common Variable Immunodeficiency-Derived B Cells. J Immunol. 2015;195:2601-11 pubmed publisher
Indrevær R, Holm K, Aukrust P, Osnes L, Naderi E, Fevang B, et al. Retinoic acid improves defective TLR9/RP105-induced immune responses in common variable immunodeficiency-derived B cells. J Immunol. 2013;191:3624-33 pubmed publisher
product information
Antigen :
CD180
Apps. Abbrev. :
FC,ICFC, IHC-F, IP
Cat # :
312902
Clone :
MHR73-11
Item :
Purified anti-human CD180 (RP105)
Isotype :
Mouse IgG1, κ
Other Names :
CD180, Radio-protective 105-kD protein, RP105
Size :
100 μg
Price (USD) :
194 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
Human RP105 complexed with mouse MD-1
Application Notes :
Additional reported applications (for the relevant formats) include: intracellular staining^1, immunoprecipitation^1, immunohistochemistry^1 of acetone-fixed frozen tissue sections, B cell activation^1, protection from apoptosis induced by radiation or dexamethasone, and induction of the costimulatory molecule CD80 (B7-1)^1. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 312913 and 312914).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA