product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-human CD158e1 (KIR3DL1, NKB1)
catalog :
312713
quantity :
25 tests
price :
193 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV421
clone name :
DX9
reactivity :
human
application :
flow cytometry
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 3c
van Erp E, Feyaerts D, Duijst M, Mulder H, Wicht O, Luytjes W, et al. Respiratory Syncytial Virus Infects Primary Neonatal and Adult Natural Killer Cells and Affects Their Antiviral Effector Function. J Infect Dis. 2019;219:723-733 pubmed publisher
  • flow cytometry; human; loading ...; fig 2b
Isitman G, Tremblay McLean A, Lisovsky I, Bruneau J, Lebouché B, Routy J, et al. NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts. PLoS ONE. 2016;11:e0164517 pubmed publisher
  • flow cytometry; human; fig 6
Yawata N, Selva K, Liu Y, Tan K, Lee A, Siak J, et al. Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection. Mucosal Immunol. 2016;9:159-70 pubmed publisher
Guo M, Sun C, Qian Y, Zhu L, Ta N, Wang G, et al. Proliferation of Highly Cytotoxic Human Natural Killer Cells by OX40L Armed NK-92 With Secretory Neoleukin-2/15 for Cancer Immunotherapy. Front Oncol. 2021;11:632540 pubmed publisher
Manser A, Scherenschlich N, Thöns C, Hengel H, Timm J, Uhrberg M. KIR Polymorphism Modulates the Size of the Adaptive NK Cell Pool in Human Cytomegalovirus-Infected Individuals. J Immunol. 2019;203:2301-2309 pubmed publisher
Ben Youssef G, Tourret M, Salou M, Ghazarian L, Houdouin V, Mondot S, et al. Ontogeny of human mucosal-associated invariant T cells and related T cell subsets. J Exp Med. 2018;215:459-479 pubmed publisher
Li H, Ivarsson M, Walker Sperling V, Subleski J, Johnson J, Wright P, et al. Identification of an elaborate NK-specific system regulating HLA-C expression. PLoS Genet. 2018;14:e1007163 pubmed publisher
Marquardt N, Ivarsson M, Blom K, Gonzalez V, Braun M, Falconer K, et al. The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education. J Immunol. 2015;195:3262-72 pubmed publisher
Lisovsky I, Isitman G, Song R, DaFonseca S, Tremblay McLean A, Lebouché B, et al. A Higher Frequency of NKG2A+ than of NKG2A- NK Cells Responds to Autologous HIV-Infected CD4 Cells irrespective of Whether or Not They Coexpress KIR3DL1. J Virol. 2015;89:9909-19 pubmed publisher
Lisovsky I, Isitman G, Bruneau J, Bernard N. Functional analysis of NK cell subsets activated by 721.221 and K562 HLA-null cells. J Leukoc Biol. 2015;97:761-7 pubmed publisher
Purdy A, Alvarez Arias D, Oshinsky J, James A, Serebriiskii I, Campbell K. The ap-2 clathrin adaptor mediates endocytosis of an inhibitory killer cell Ig-like receptor in human NK cells. J Immunol. 2014;193:4675-83 pubmed publisher
Boudreau J, Le Luduec J, Hsu K. Development of a novel multiplex PCR assay to detect functional subtypes of KIR3DL1 alleles. PLoS ONE. 2014;9:e99543 pubmed publisher
Terszowski G, Klein C, Stern M. KIR/HLA interactions negatively affect rituximab- but not GA101 (obinutuzumab)-induced antibody-dependent cellular cytotoxicity. J Immunol. 2014;192:5618-24 pubmed publisher
Lichterfeld M, Kavanagh D, Williams K, Moza B, Mui S, Miura T, et al. A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells. J Exp Med. 2007;204:2813-24 pubmed
Pascal V, Yamada E, Martin M, Alter G, Altfeld M, Metcalf J, et al. Detection of KIR3DS1 on the cell surface of peripheral blood NK cells facilitates identification of a novel null allele and assessment of KIR3DS1 expression during HIV-1 infection. J Immunol. 2007;179:1625-33 pubmed
product information
Antigen :
CD158e1
Apps. Abbrev. :
FC
Cat # :
312713
Clone :
DX9
Item :
Brilliant Violet 421™ anti-human CD158e1 (KIR3DL1, NKB1)
Isotype :
Mouse IgG1, κ
Other Names :
NKAT3, NKB1, KIR-NKB1, p70
Size :
25 tests
Price (USD) :
193 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV421
Immunogen :
Human NK cell clone VL186-1.6
Application Notes :
The DX9 antibody reacts with the KIR (killer cell inhibitory receptor) designated NKB1 or KIR3DL1. Additional reported applications (for the relevant formats) include: immunoprecipitation^1 and restoring the NK cell cytotoxicity^4,8. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 312710).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA