product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human CD158e1 (KIR3DL1, NKB1)
catalog :
312708
quantity :
100 tests
price :
237 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
DX9
reactivity :
human
application :
flow cytometry
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 6
Yawata N, Selva K, Liu Y, Tan K, Lee A, Siak J, et al. Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection. Mucosal Immunol. 2016;9:159-70 pubmed publisher
  • flow cytometry; human
Luetke Eversloh M, Hammer Q, Durek P, Nordström K, Gasparoni G, Pink M, et al. Human cytomegalovirus drives epigenetic imprinting of the IFNG locus in NKG2Chi natural killer cells. PLoS Pathog. 2014;10:e1004441 pubmed publisher
Bennstein S, Weinhold S, Manser A, Scherenschlich N, Noll A, Raba K, et al. Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells. elife. 2020;9: pubmed publisher
Lu H, Jin L, Huang H, Ha S, Yang H, Chang R, et al. Trophoblast-derived CXCL12 promotes CD56bright CD82- CD29+ NK cell enrichment in the decidua. Am J Reprod Immunol. 2020;83: pubmed publisher
Poznanski S, Nham T, Chew M, Lee A, Hammill J, Fan I, et al. Expanded CD56superbrightCD16+ NK Cells from Ovarian Cancer Patients Are Cytotoxic against Autologous Tumor in a Patient-Derived Xenograft Murine Model. Cancer Immunol Res. 2018;6:1174-1185 pubmed publisher
Purdy A, Alvarez Arias D, Oshinsky J, James A, Serebriiskii I, Campbell K. The ap-2 clathrin adaptor mediates endocytosis of an inhibitory killer cell Ig-like receptor in human NK cells. J Immunol. 2014;193:4675-83 pubmed publisher
O Connor G, Yamada E, Rampersaud A, Thomas R, Carrington M, McVicar D. Analysis of binding of KIR3DS1*014 to HLA suggests distinct evolutionary history of KIR3DS1. J Immunol. 2011;187:2162-71 pubmed publisher
Berg M, Lundqvist A, McCoy P, Samsel L, Fan Y, Tawab A, et al. Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells. Cytotherapy. 2009;11:341-55 pubmed publisher
Thomas R, Yamada E, Alter G, Martin M, Bashirova A, Norman P, et al. Novel KIR3DL1 alleles and their expression levels on NK cells: convergent evolution of KIR3DL1 phenotype variation?. J Immunol. 2008;180:6743-50 pubmed
Lichterfeld M, Kavanagh D, Williams K, Moza B, Mui S, Miura T, et al. A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells. J Exp Med. 2007;204:2813-24 pubmed
Pascal V, Yamada E, Martin M, Alter G, Altfeld M, Metcalf J, et al. Detection of KIR3DS1 on the cell surface of peripheral blood NK cells facilitates identification of a novel null allele and assessment of KIR3DS1 expression during HIV-1 infection. J Immunol. 2007;179:1625-33 pubmed
product information
Antigen :
CD158e1
Apps. Abbrev. :
FC
Cat # :
312708
Clone :
DX9
Item :
PE anti-human CD158e1 (KIR3DL1, NKB1)
Isotype :
Mouse IgG1, κ
Other Names :
NKAT3, NKB1, KIR-NKB1, p70
Size :
100 tests
Price (USD) :
237 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Immunogen :
Human NK cell clone VL186-1.6
Application Notes :
The DX9 antibody reacts with the KIR (killer cell inhibitory receptor) designated NKB1 or KIR3DL1. Additional reported applications (for the relevant formats) include: immunoprecipitation^1 and restoring the NK cell cytotoxicity^4,8. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 312710).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA