product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD158b/j (KIR2DL2/L3/S2)
catalog :
312611
quantity :
25 tests
price :
142 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
DX27
reactivity :
human
application :
flow cytometry
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 1e
Cuff A, Robertson F, Stegmann K, Pallett L, Maini M, Davidson B, et al. Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation. J Immunol. 2016;197:4283-4291 pubmed
Sitlinger A, Deal M, Garcia E, Thompson D, Stewart T, MacDonald G, et al. Physiological Fitness and the Pathophysiology of Chronic Lymphocytic Leukemia (CLL). Cells. 2021;10: pubmed publisher
Shu L, Zhong L, Xiao Y, Wu X, Liu Y, Jiang X, et al. Neutrophil elastase triggers the development of autoimmune diabetes by exacerbating innate immune responses in pancreatic islets of non-obese diabetic mice. Clin Sci (Lond). 2020;134:1679-1696 pubmed publisher
Kawabe T, Yi J, Kawajiri A, Hilligan K, Fang D, Ishii N, et al. Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state. Nat Commun. 2020;11:3366 pubmed publisher
Choi J, Maeng H, Lee S, Kim Y, Kim D, Lee H, et al. Diagnostic value of peripheral blood immune profiling in colorectal cancer. Ann Surg Treat Res. 2018;94:312-321 pubmed publisher
Li B, Wang Z, Wu H, Xue M, Lin P, Wang S, et al. Epigenetic Regulation of CXCL12 Plays a Critical Role in Mediating Tumor Progression and the Immune Response In Osteosarcoma. Cancer Res. 2018;78:3938-3953 pubmed publisher
Lubaki N, Younan P, Santos R, Meyer M, Iampietro M, Koup R, et al. The Ebola Interferon Inhibiting Domains Attenuate and Dysregulate Cell-Mediated Immune Responses. PLoS Pathog. 2016;12:e1006031 pubmed publisher
Ahmad F, Hong H, Jäckel M, Jablonka A, Lu I, Bhatnagar N, et al. High frequencies of polyfunctional CD8+ NK cells in chronic HIV-1 infection are associated with slower disease progression. J Virol. 2014;88:12397-408 pubmed publisher
product information
Antigen :
CD158b/j
Apps. Abbrev. :
FC
Cat # :
312611
Clone :
DX27
Item :
APC anti-human CD158b/j (KIR2DL2/L3/S2)
Isotype :
Mouse IgG2a, κ
Other Names :
CD158b1 (KIR2DL2, p58.2), CD158b2 (KIR2DL3, p58.3), CD158j (KIR2DS2, p50.2), KIR-NKAT2
Size :
25 tests
Price (USD) :
142 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Application Notes :
The DX27 monoclonal antibody reacts with a common epitope of KIR2DL2 (CD158b1, p58.2), KIR2DL3 (CD158b2, p58.3), and KIR2DS2 (CD158j, p50.2). Additional reported applications (for the relevant formats) include: restoring the NK cell cytotoxicity^1,5.This clone has been tested in-house and determined to not be suitable for applications in immunohistochemistry of paraffin-embedded tissue sections (IHC-P).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA