Purified anti-human CD158b/j (KIR2DL2/L3/S2) | BioLegend 312602 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-human CD158b/j (KIR2DL2/L3/S2)

catalog :

312602

quantity :

100 μg

price :

112 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DX27

reactivity :

human, mouse

application :

flow cytometry, other

more info or order :

BioLegend product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
other; mouse	Tseng H, Xiong W, Badeti S, Yang Y, Ma M, Liu T, et al. Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma. Nat Commun. 2020;11:4810 pubmed publisher
flow cytometry; human; loading ...; fig 4e	Nguyen R, Houston J, Chan W, Finkelstein D, Dyer M. The role of interleukin-2, all-trans retinoic acid, and natural killer cells: surveillance mechanisms in anti-GD2 antibody therapy in neuroblastoma. Cancer Immunol Immunother. 2018;67:615-626 pubmed publisher
flow cytometry; human; fig 1e	Cuff A, Robertson F, Stegmann K, Pallett L, Maini M, Davidson B, et al. Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation. J Immunol. 2016;197:4283-4291 pubmed
flow cytometry; human; loading ...; fig s1	Landtwing V, Raykova A, Pezzino G, Beziat V, Marcenaro E, Graf C, et al. Cognate HLA absence in trans diminishes human NK cell education. J Clin Invest. 2016;126:3772-3782 pubmed publisher
	Merlo L, Bowers J, Stefanoni T, Getts R, Mandik Nayak L. B-Cell-Targeted 3DNA Nanotherapy Against Indoleamine 2,3-Dioxygenase 2 (IDO2) Ameliorates Autoimmune Arthritis in a Preclinical Model. Clin Pathol. 2020;13:2632010X20951812 pubmed publisher
	Liang J, Wang H, Ding W, Huang J, Zhou X, Wang H, et al. Nanoparticle-enhanced chemo-immunotherapy to trigger robust antitumor immunity. Sci Adv. 2020;6:eabc3646 pubmed publisher
	Park H, Lim S, Hwang J, Zhang W, You S, Jin J. Cancer immunotherapy using a polysaccharide from Codium fragile in a murine model. Oncoimmunology. 2020;9:1772663 pubmed publisher
	Flosbach M, Oberle S, Scherer S, Zecha J, von Hoesslin M, Wiede F, et al. PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells. Cell Rep. 2020;32:107957 pubmed publisher
	Lebel M, Coutelier M, Galipeau M, Kleinman C, Moon J, Melichar H. Differential expression of tissue-restricted antigens among mTEC is associated with distinct autoreactive T cell fates. Nat Commun. 2020;11:3734 pubmed publisher
	Baumann D, Hägele T, Mochayedi J, Drebant J, Vent C, Blobner S, et al. Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy. Nat Commun. 2020;11:2176 pubmed publisher
	Somerville T, Biffi G, Da ler Plenker J, Hur S, He X, Vance K, et al. Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation. elife. 2020;9: pubmed publisher
	Ferrari de Andrade L, Kumar S, Luoma A, Ito Y, Alves da Silva P, Pan D, et al. Inhibition of MICA and MICB Shedding Elicits NK-Cell-Mediated Immunity against Tumors Resistant to Cytotoxic T Cells. Cancer Immunol Res. 2020;8:769-780 pubmed publisher
	Chew H, De Lima P, Gonzalez Cruz J, Banushi B, Echejoh G, Hu L, et al. Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell. 2020;180:895-914.e27 pubmed publisher
	Lavoie S, Chun E, Bae S, Brennan C, Gallini Comeau C, Lang J, et al. Expression of Free Fatty Acid Receptor 2 by Dendritic Cells Prevents Their Expression of Interleukin 27 and Is Required for Maintenance of Mucosal Barrier and Immune Response Against Colorectal Tumors in Mice. Gastroenterology. 2020;158:1359-1372.e9 pubmed publisher
	Lai N, Musser M, Pinho Ribeiro F, Baral P, Jacobson A, Ma P, et al. Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense. Cell. 2020;180:33-49.e22 pubmed publisher
	Vono M, Eberhardt C, Auderset F, Mastelic Gavillet B, Lemeille S, Christensen D, et al. Maternal Antibodies Inhibit Neonatal and Infant Responses to Vaccination by Shaping the Early-Life B Cell Repertoire within Germinal Centers. Cell Rep. 2019;28:1773-1784.e5 pubmed publisher
	Niu C, Li M, Zhu S, Chen Y, Zhou L, Xu D, et al. Decitabine Inhibits Gamma Delta T Cell Cytotoxicity by Promoting KIR2DL2/3 Expression. Front Immunol. 2018;9:617 pubmed publisher
	Zal B, Kaski J, Akiyu J, Cole D, Arno G, Poloniecki J, et al. Differential pathways govern CD4+ CD28- T cell proinflammatory and effector responses in patients with coronary artery disease. J Immunol. 2008;181:5233-41 pubmed

product information

Antigen :

CD158b/j

Apps. Abbrev. :

Cat # :

312602

Clone :

DX27

Item :

Purified anti-human CD158b/j (KIR2DL2/L3/S2)

Isotype :

Mouse IgG2a, κ

Other Names :

CD158b1 (KIR2DL2, p58.2), CD158b2 (KIR2DL3, p58.3), CD158j (KIR2DS2, p50.2), KIR-NKAT2

Size :

100 μg

Price (USD) :

112 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Application Notes :

The DX27 monoclonal antibody reacts with a common epitope of KIR2DL2 (CD158b1, p58.2), KIR2DL3 (CD158b2, p58.3), and KIR2DS2 (CD158j, p50.2). Additional reported applications (for the relevant formats) include: restoring the NK cell cytotoxicity^1,5.This clone has been tested in-house and determined to not be suitable for applications in immunohistochemistry of paraffin-embedded tissue sections (IHC-P).;

more info or order :

BioLegend product webpage