product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human CD137L (4-1BB Ligand)
catalog :
311502
quantity :
100 μg
price :
129 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5F4
reactivity :
human
application :
flow cytometry
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 1
Lee Chang C, Bodogai M, Moritoh K, Chen X, Wersto R, Sen R, et al. Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers. J Immunol. 2016;196:3385-97 pubmed publisher
  • flow cytometry; human; fig 6
Jutz S, Leitner J, Schmetterer K, Doel Perez I, Majdic O, Grabmeier Pfistershammer K, et al. Assessment of costimulation and coinhibition in a triple parameter T cell reporter line: Simultaneous measurement of NF-κB, NFAT and AP-1. J Immunol Methods. 2016;430:10-20 pubmed publisher
  • flow cytometry; human
Lee Chang C, Bodogai M, Moritoh K, Olkhanud P, Chan A, Croft M, et al. Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity. Blood. 2014;124:1450-9 pubmed publisher
Vidard L, Dureuil C, Baudhuin J, Vescovi L, Durand L, Sierra V, et al. CD137 (4-1BB) Engagement Fine-Tunes Synergistic IL-15- and IL-21-Driven NK Cell Proliferation. J Immunol. 2019;: pubmed publisher
Eriksson E, Milenova I, Wenthe J, Ståhle M, Leja Jarblad J, Ullenhag G, et al. Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus. Clin Cancer Res. 2017;23:5846-5857 pubmed publisher
Ho W, Pang W, Chong S, Castella A, Al Salam S, Tan T, et al. Expression of CD137 on Hodgkin and Reed-Sternberg cells inhibits T-cell activation by eliminating CD137 ligand expression. Cancer Res. 2013;73:652-61 pubmed publisher
product information
Antigen :
CD137L
Apps. Abbrev. :
FC
Cat # :
311502
Clone :
5F4
Item :
Purified anti-human CD137L (4-1BB Ligand)
Isotype :
Mouse IgG1, κ
Other Names :
4-1BBL, CD137L, TNFSF9, 41BBL
Size :
100 μg
Price (USD) :
129 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Application Notes :
For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 311504) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA