PE/Cyanine7 anti-human HLA-A,B,C | BioLegend 311430 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Cyanine7 anti-human HLA-A,B,C

catalog :

311430

quantity :

100 tests

price :

288 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

W6/32

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig s1	Poletto E, Colella P, Pimentel Vera L, Khan S, Tomatsu S, Baldo G, et al. Improved engraftment and therapeutic efficacy by human genome-edited hematopoietic stem cells with Busulfan-based myeloablation. Mol Ther Methods Clin Dev. 2022;25:392-409 pubmed publisher
	Glaser V, Flugel C, Kath J, Du W, Drosdek V, Franke C, et al. Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells. Genome Biol. 2023;24:89 pubmed publisher
	Campbell K, Colacino J, Puttabyatappa M, Dou J, Elkin E, Hammoud S, et al. Placental cell type deconvolution reveals that cell proportions drive preeclampsia gene expression differences. Commun Biol. 2023;6:264 pubmed publisher
	Herter J, Kiljan M, Kunze S, Reinscheid M, Ibruli O, Cai J, et al. Influence of chemoradiation on the immune microenvironment of cervical cancer patients. Strahlenther Onkol. 2023;199:121-130 pubmed publisher
	Rodems T, Heninger E, Stahlfeld C, Gilsdorf C, Carlson K, Kircher M, et al. Reversible epigenetic alterations regulate class I HLA loss in prostate cancer. Commun Biol. 2022;5:897 pubmed publisher
	Song S, Manook M, Kwun J, Jackson A, Knechtle S, Kelsoe G. Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells. Front Immunol. 2021;12:705140 pubmed publisher
	Kalbasi A, Tariveranmoshabad M, Hakimi K, Kremer S, Campbell K, Funes J, et al. Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma. Sci Transl Med. 2020;12: pubmed publisher
	Klichinsky M, Ruella M, Shestova O, Lu X, Best A, Zeeman M, et al. Human chimeric antigen receptor macrophages for cancer immunotherapy. Nat Biotechnol. 2020;38:947-953 pubmed publisher
	Yan L, Lau S, Poh C, Chan V, Chan M, Peiris M, et al. Heterosubtypic Protection Induced by a Live Attenuated Influenza Virus Vaccine Expressing Galactose-α-1,3-Galactose Epitopes in Infected Cells. MBio. 2020;11: pubmed publisher
	Kalaora S, Lee J, Barnea E, Levy R, Greenberg P, Alon M, et al. Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma. Nat Commun. 2020;11:896 pubmed publisher
	Zhang W, Kwak M, Park H, Okimura T, Oda T, Lee P, et al. Activation of Human Dendritic Cells by Ascophyllan Purified from Ascophyllum nodosum. Mar Drugs. 2019;17: pubmed publisher
	Huang L, Malu S, McKenzie J, Andrews M, Talukder A, Tieu T, et al. The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression. Clin Cancer Res. 2018;24:3366-3376 pubmed publisher
	Bolton D, McGinnis K, Finak G, Chattopadhyay P, Gottardo R, Roederer M. Combined single-cell quantitation of host and SIV genes and proteins ex vivo reveals host-pathogen interactions in individual cells. PLoS Pathog. 2017;13:e1006445 pubmed publisher
	Robinson P, Lau E, Keith P, Lau M, Thomas G, Bradbury L, et al. ERAP2 functional knockout in humans does not alter surface heavy chains or HLA-B27, inflammatory cytokines or endoplasmic reticulum stress markers. Ann Rheum Dis. 2015;74:2092-5 pubmed publisher

product information

Antigen :

HLA-A

Apps. Abbrev. :

Cat # :

311430

Clone :

W6/32

Item :

PE/Cyanine7 anti-human HLA-A,B,C

Isotype :

Mouse IgG2a, κ

Other Names :

Major Histocompatibility Class I, MHC class I

Size :

100 tests

Price (USD) :

288 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PE_CYANINE7

Application Notes :

Clone W6/32 recognizes residues in the N terminus of the human ß2-microglobulin molecule^21.Additional reported applications (for the relevant formats) include: immunoprecipitaton^2, Western blotting (non-reducing)^3, immunohistochemical staining of acetone-fixed frozen tissue sections^4,5, blocking^6,7, inhibition of NK cell-mediated lysis^10, and activation^8,9. Clone W6/32 has been reported not to be suitable for immunohistochemistry on paraffin sections^17. The LEAF™ purified antibody (Endotoxin < 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 311428) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin < 0.01 EU/µg).;

more info or order :

BioLegend product webpage