Pacific Blue™ anti-human HLA-A,B,C | BioLegend 311418 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Pacific Blue™ anti-human HLA-A,B,C

catalog :

311418

quantity :

100 μg

price :

265 USD

clonality :

monoclonal

host :

mouse

conjugate :

Pacific Blue

clone name :

W6/32

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 13

Reference
Parker R, Partridge T, Wormald C, Kawahara R, Stalls V, Aggelakopoulou M, et al. Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells. Cell Rep. 2021;35:109179 pubmed publisher
Io S, Kabata M, Iemura Y, Semi K, Morone N, Minagawa A, et al. Capturing human trophoblast development with naive pluripotent stem cells in vitro. Cell Stem Cell. 2021;28:1023-1039.e13 pubmed publisher
Bettencourt P, Müller J, Nicastri A, Cantillon D, Madhavan M, Charles P, et al. Identification of antigens presented by MHC for vaccines against tuberculosis. NPJ Vaccines. 2020;5:2 pubmed publisher
van Stigt Thans T, Akko J, Niehrs A, Garcia Beltran W, Richert L, Stürzel C, et al. Primary HIV-1 Strains Use Nef To Downmodulate HLA-E Surface Expression. J Virol. 2019;93: pubmed publisher
Xu H, Wang B, Ono M, Kagita A, Fujii K, Sasakawa N, et al. Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility. Cell Stem Cell. 2019;: pubmed publisher
Lee H, Kim Y, Sim C, Heo S, Song I, Park H, et al. Expansion of tumor-infiltrating lymphocytes and their potential for application as adoptive cell transfer therapy in human breast cancer. Oncotarget. 2017;8:113345-113359 pubmed publisher
Rusconi M, Gerardi F, Santus W, Lizio A, Sansone V, Lunetta C, et al. Inflammatory role of dendritic cells in Amyotrophic Lateral Sclerosis revealed by an analysis of patients' peripheral blood. Sci Rep. 2017;7:7853 pubmed publisher
de Witte S, Merino A, Franquesa M, Strini T, van Zoggel J, Korevaar S, et al. Cytokine treatment optimises the immunotherapeutic effects of umbilical cord-derived MSC for treatment of inflammatory liver disease. Stem Cell Res Ther. 2017;8:140 pubmed publisher
Clutton G, Xu Y, Baldoni P, Mollan K, Kirchherr J, Newhard W, et al. The differential short- and long-term effects of HIV-1 latency-reversing agents on T cell function. Sci Rep. 2016;6:30749 pubmed publisher
Martrus G, Niehrs A, Cornelis R, Rechtien A, Garcia Beltran W, Lutgehetmann M, et al. Kinetics of HIV-1 Latency Reversal Quantified on the Single-Cell Level Using a Novel Flow-Based Technique. J Virol. 2016;90:9018-28 pubmed publisher
Kotsiou E, Okosun J, Besley C, Iqbal S, Matthews J, Fitzgibbon J, et al. TNFRSF14 aberrations in follicular lymphoma increase clinically significant allogeneic T-cell responses. Blood. 2016;128:72-81 pubmed publisher
Delitto D, Perez C, Han S, Gonzalo D, Pham K, Knowlton A, et al. Downstream mediators of the intratumoral interferon response suppress antitumor immunity, induce gemcitabine resistance and associate with poor survival in human pancreatic cancer. Cancer Immunol Immunother. 2015;64:1553-63 pubmed publisher
Manuel S, Sehgal M, Khan Z, Goedert J, Betts M, Jain P. An altered maturation and adhesion phenotype of dendritic cells in diseased individuals compared to asymptomatic carriers of human T cell leukemia virus type 1. AIDS Res Hum Retroviruses. 2013;29:1273-85 pubmed publisher

product information

Antigen :

HLA-A

Apps. Abbrev. :

Cat # :

311418

Clone :

W6/32

Item :

Pacific Blue™ anti-human HLA-A,B,C

Isotype :

Mouse IgG2a, κ

Other Names :

Major Histocompatibility Class I, MHC class I

Size :

100 μg

Price (USD) :

265 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Application Notes :

Clone W6/32 recognizes residues in the N terminus of the human ß2-microglobulin molecule^21.Additional reported applications (for the relevant formats) include: immunoprecipitaton^2, Western blotting (non-reducing)^3, immunohistochemical staining of acetone-fixed frozen tissue sections^4,5, blocking^6,7, inhibition of NK cell-mediated lysis^10, and activation^8,9. Clone W6/32 has been reported not to be suitable for immunohistochemistry on paraffin sections^17. The LEAF™ purified antibody (Endotoxin < 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 311428) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin < 0.01 EU/µg).;

more info or order :

BioLegend product webpage