product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Dazzle™ 594 anti-human CD154 (CD40L)
catalog :
310839
quantity :
25 tests
price :
147 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
24-31
reactivity :
human
application :
flow cytometry
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 3
Steindor M, Nkwouano V, Mayatepek E, Mackenzie C, Schramm D, Jacobsen M. Rapid detection and immune characterization of Mycobacterium abscessus infection in cystic fibrosis patients. PLoS ONE. 2015;10:e0119737 pubmed publisher
Rydyznski Moderbacher C, Kim C, Mateus J, Plested J, Zhu M, Cloney Clark S, et al. NVX-CoV2373 vaccination induces functional SARS-CoV-2-specific CD4+ and CD8+ T cell responses. J Clin Invest. 2022;132: pubmed publisher
Vanshylla K, Fan C, Wunsch M, Poopalasingam N, Meijers M, Kreer C, et al. Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers. Cell Host Microbe. 2022;30:69-82.e10 pubmed publisher
Peluso M, Deitchman A, Torres L, Iyer N, Munter S, Nixon C, et al. Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms. Cell Rep. 2021;36:109518 pubmed publisher
Cohen C, Li A, Hachim A, Hui D, Kwan M, Tsang O, et al. SARS-CoV-2 specific T cell responses are lower in children and increase with age and time after infection. Nat Commun. 2021;12:4678 pubmed publisher
Rydyznski Moderbacher C, Ramirez S, Dan J, Grifoni A, Hastie K, Weiskopf D, et al. Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity. Cell. 2020;183:996-1012.e19 pubmed publisher
Bourges C, Groff A, Burren O, Gerhardinger C, Mattioli K, Hutchinson A, et al. Resolving mechanisms of immune-mediated disease in primary CD4 T cells. EMBO Mol Med. 2020;12:e12112 pubmed publisher
Weed D, Zilio S, Reis I, Sargi Z, Abouyared M, Gomez Fernandez C, et al. The Reversal of Immune Exclusion Mediated by Tadalafil and an Anti-tumor Vaccine Also Induces PDL1 Upregulation in Recurrent Head and Neck Squamous Cell Carcinoma: Interim Analysis of a Phase I Clinical Trial. Front Immunol. 2019;10:1206 pubmed publisher
Doorduijn E, Sluijter M, Querido B, Oliveira C, Achour A, Ossendorp F, et al. TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors. J Clin Invest. 2016;126:784-94 pubmed publisher
Matus Nicodemos R, Vavassori S, Castro Faix M, Valentin Acevedo A, Singh K, Marcelli V, et al. Polypyrimidine tract-binding protein is critical for the turnover and subcellular distribution of CD40 ligand mRNA in CD4+ T cells. J Immunol. 2011;186:2164-71 pubmed publisher
Zhang A, Colmenero P, Purath U, Teixeira de Matos C, Hueber W, Klareskog L, et al. Natural killer cells trigger differentiation of monocytes into dendritic cells. Blood. 2007;110:2484-93 pubmed
product information
Antigen :
CD154
Apps. Abbrev. :
FC
Cat # :
310839
Clone :
24-31
Item :
PE/Dazzle™ 594 anti-human CD154 (CD40L)
Isotype :
Mouse IgG1, κ
Other Names :
CD40L, gp39, TRAP, T-BAM, TNFSF5
Size :
25 tests
Price (USD) :
147 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE_DZL594
Application Notes :
Additional reported applications (for the relevant formats) include: immunofluorescence microscopy^1,3 and blocking of T cell-dependent B cell differentiation^1,2,4,5. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 310812). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 310828) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA