Brilliant Violet 421™ anti-human CD154 (CD40L) | BioLegend 310824 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 421™ anti-human CD154 (CD40L)

catalog :

310824

quantity :

100 tests

price :

435 USD

clonality :

monoclonal

host :

mouse

conjugate :

BV421

clone name :

24-31

reactivity :

human

application :

flow cytometry, immunohistochemistry - frozen section

more info or order :

BioLegend product webpage

citations: 13

Reference
Adamo S, Gao Y, Sekine T, Mily A, Wu J, Storg xe4 rd E, et al. Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox. Cell Host Microbe. 2023;31:928-936.e4 pubmed publisher
Gao F, Mallajosyula V, Arunachalam P, van der Ploeg K, Manohar M, R xf6 ltgen K, et al. Spheromers reveal robust T cell responses to the Pfizer/BioNTech vaccine and attenuated peripheral CD8+ T cell responses post SARS-CoV-2 infection. Immunity. 2023;56:864-878.e4 pubmed publisher
Gao Y, Cai C, Wullimann D, Niessl J, Rivera Ballesteros O, Chen P, et al. Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination. Immunity. 2022;55:1732-1746.e5 pubmed publisher
Romero Olmedo A, Schulz A, Hochstätter S, Das Gupta D, Virta I, Hirseland H, et al. Induction of robust cellular and humoral immunity against SARS-CoV-2 after a third dose of BNT162b2 vaccine in previously unresponsive older adults. Nat Microbiol. 2022;7:195-199 pubmed publisher
Cossarizza A, Chang H, Radbruch A, Abrignani S, Addo R, Akdis M, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition). Eur J Immunol. 2021;51:2708-3145 pubmed publisher
Arunachalam P, Scott M, Hagan T, Li C, Feng Y, Wimmers F, et al. Systems vaccinology of the BNT162b2 mRNA vaccine in humans. Nature. 2021;596:410-416 pubmed publisher
Ferreira Gomes M, Kruglov A, Durek P, Heinrich F, Tizian C, Heinz G, et al. SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself. Nat Commun. 2021;12:1961 pubmed publisher
Wenthe J, Naseri S, Labani Motlagh A, Enblad G, Wikstrom K, Eriksson E, et al. Boosting CAR T-cell responses in lymphoma by simultaneous targeting of CD40/4-1BB using oncolytic viral gene therapy. Cancer Immunol Immunother. 2021;70:2851-2865 pubmed publisher
Tesch S, Abdirama D, Grießbach A, Brand H, Goerlich N, Humrich J, et al. Identification and characterization of antigen-specific CD4+ T cells targeting renally expressed antigens in human lupus nephritis with two independent methods. Sci Rep. 2020;10:21312 pubmed publisher
Braun J, Loyal L, Frentsch M, Wendisch D, Georg P, Kurth F, et al. SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19. Nature. 2020;587:270-274 pubmed publisher
Sayin I, Radtke A, Vella L, Jin W, Wherry E, Buggert M, et al. Spatial distribution and function of T follicular regulatory cells in human lymph nodes. J Exp Med. 2018;215:1531-1542 pubmed publisher
Warthan M, Washington S, Franzese S, Ramus R, Kim K, York T, et al. The role of endoplasmic reticulum aminopeptidase 2 in modulating immune detection of choriocarcinoma. Biol Reprod. 2018;98:309-322 pubmed publisher
Eriksson E, Moreno R, Milenova I, Liljenfeldt L, Dieterich L, Christiansson L, et al. Activation of myeloid and endothelial cells by CD40L gene therapy supports T-cell expansion and migration into the tumor microenvironment. Gene Ther. 2017;24:92-103 pubmed publisher

product information

Antigen :

CD154

Apps. Abbrev. :

FC, IHC-F

Cat # :

310824

Clone :

24-31

Item :

Brilliant Violet 421™ anti-human CD154 (CD40L)

Isotype :

Mouse IgG1, κ

Other Names :

CD40L, gp39, TRAP, T-BAM, TNFSF5

Size :

100 tests

Price (USD) :

435 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

BV421

Application Notes :

Additional reported applications (for the relevant formats) include: immunofluorescence microscopy^1,3 and blocking of T cell-dependent B cell differentiation^1,2,4,5. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 310812). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 310828) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;

more info or order :

BioLegend product webpage