product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human CD154 (CD40L)
catalog :
310805
quantity :
25 tests
price :
131 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
24-31
reactivity :
human
application :
flow cytometry
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 3b
Cui X, Ma C, Vasudevaraja V, Serrano J, Tong J, Peng Y, et al. Dissecting the immunosuppressive tumor microenvironments in Glioblastoma-on-a-Chip for optimized PD-1 immunotherapy. elife. 2020;9: pubmed publisher
  • flow cytometry; human; 1:100; loading ...; fig e8
Yang W, Lee K, Srivastava R, Kuo F, Krishna C, Chowell D, et al. Immunogenic neoantigens derived from gene fusions stimulate T cell responses. Nat Med. 2019;25:767-775 pubmed publisher
  • flow cytometry; human; fig 3
Steindor M, Nkwouano V, Mayatepek E, Mackenzie C, Schramm D, Jacobsen M. Rapid detection and immune characterization of Mycobacterium abscessus infection in cystic fibrosis patients. PLoS ONE. 2015;10:e0119737 pubmed publisher
Wang Y, Song W, Xu Q, Liu Y, Liu H, Guo R, et al. Adjuvant DNA vaccine pNMM promotes enhanced specific immunity and anti-tumor effects. Hum Vaccin Immunother. 2023;19:2202127 pubmed publisher
Babl N, Hofbauer J, Matos C, Voll F, Menevse A, Rechenmacher M, et al. Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model. Front Oncol. 2023;13:1107484 pubmed publisher
Pandit H, Valentin A, Angel M, Deléage C, Bergamaschi C, Bear J, et al. Step-dose IL-7 treatment promotes systemic expansion of T cells and alters immune cell landscape in blood and lymph nodes. iScience. 2023;26:105929 pubmed publisher
Lim J, Tan A, Bertoletti A. Protocol to detect antigen-specific nasal-resident T cells in humans. STAR Protoc. 2023;4:101995 pubmed publisher
Yu E, Wang E, Garrigan E, Sutherland A, Khalil N, Kearns K, et al. Ex vivo assays show human gamma-delta T cells specific for common allergens are Th1-polarized in allergic donors. Cell Rep Methods. 2022;2:100350 pubmed publisher
Veatch J, Lee S, Shasha C, Singhi N, Szeto J, Moshiri A, et al. Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function. Cancer Cell. 2022;40:393-409.e9 pubmed publisher
Collora J, Liu R, Pinto Santini D, Ravindra N, Ganoza C, Lama J, et al. Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones. Immunity. 2022;55:1013-1031.e7 pubmed publisher
Gu C, Upchurch K, Horton J, Wiest M, Zurawski S, Millard M, et al. Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells. Front Immunol. 2021;12:678036 pubmed publisher
Beziat V, Rapaport F, Hu J, Titeux M, Bonnet des Claustres M, Bourgey M, et al. Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy. Cell. 2021;184:3812-3828.e30 pubmed publisher
Biondi B, Mohanty S, Wyk B, Montgomery R, Shaw A, Springer S. Design and implementation of a prospective cohort study of persons living with and without HIV infection who are initiating medication treatment for opioid use disorder. Contemp Clin Trials Commun. 2021;21:100704 pubmed publisher
Zhang J, Wu Q, Liu Z, Wang Q, Wu J, Hu Y, et al. Spike-specific circulating T follicular helper cell and cross-neutralizing antibody responses in COVID-19-convalescent individuals. Nat Microbiol. 2021;6:51-58 pubmed publisher
Dyson M, Masters E, Pazeraitis D, Perera R, Syrjänen J, Surade S, et al. Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries. MAbs. 2020;12:1829335 pubmed publisher
Meckiff B, Ramírez Suástegui C, Fajardo V, Chee S, Kusnadi A, Simon H, et al. Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4+ T Cells in COVID-19. Cell. 2020;183:1340-1353.e16 pubmed publisher
Lakshmikanth T, Muhammad S, Olin A, Chen Y, Mikes J, Fagerberg L, et al. Human Immune System Variation during 1 Year. Cell Rep. 2020;32:107923 pubmed publisher
Ahmed R, Omidian Z, Giwa A, Cornwell B, Majety N, Bell D, et al. A Public BCR Present in a Unique Dual-Receptor-Expressing Lymphocyte from Type 1 Diabetes Patients Encodes a Potent T Cell Autoantigen. Cell. 2019;177:1583-1599.e16 pubmed publisher
Shifrut E, Carnevale J, Tobin V, Roth T, Woo J, Bui C, et al. Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function. Cell. 2018;175:1958-1971.e15 pubmed publisher
Karnell J, Karnell F, Stephens G, Rajan B, Morehouse C, Li Y, et al. Mycophenolic acid differentially impacts B cell function depending on the stage of differentiation. J Immunol. 2011;187:3603-12 pubmed publisher
Matus Nicodemos R, Vavassori S, Castro Faix M, Valentin Acevedo A, Singh K, Marcelli V, et al. Polypyrimidine tract-binding protein is critical for the turnover and subcellular distribution of CD40 ligand mRNA in CD4+ T cells. J Immunol. 2011;186:2164-71 pubmed publisher
Kuchen S, Robbins R, Sims G, Sheng C, Phillips T, Lipsky P, et al. Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration. J Immunol. 2007;179:5886-96 pubmed
Zhang A, Colmenero P, Purath U, Teixeira de Matos C, Hueber W, Klareskog L, et al. Natural killer cells trigger differentiation of monocytes into dendritic cells. Blood. 2007;110:2484-93 pubmed
product information
Antigen :
CD154
Apps. Abbrev. :
FC
Cat # :
310805
Clone :
24-31
Item :
PE anti-human CD154 (CD40L)
Isotype :
Mouse IgG1, κ
Other Names :
CD40L, gp39, TRAP, T-BAM, TNFSF5
Size :
25 tests
Price (USD) :
131 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Application Notes :
Additional reported applications (for the relevant formats) include: immunofluorescence microscopy^1,3 and blocking of T cell-dependent B cell differentiation^1,2,4,5. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 310812). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 310828) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA