PE/Dazzle™ 594 anti-human CD137 (4-1BB) | BioLegend 309826 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Dazzle™ 594 anti-human CD137 (4-1BB)

catalog :

309826

quantity :

100 tests

price :

323 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

4B4-1

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1b	Di Blasi D, Boldanova T, Mori L, Terracciano L, Heim M, De Libero G. Unique T-Cell Populations Define Immune-Inflamed Hepatocellular Carcinoma. Cell Mol Gastroenterol Hepatol. 2020;9:195-218 pubmed publisher
	Sannier G, Nicolas A, Dub xe9 M, Marchitto L, Nayrac M, Tastet O, et al. A third SARS-CoV-2 mRNA vaccine dose in people receiving hemodialysis overcomes B cell defects but elicits a skewed CD4+ T cell profile. Cell Rep Med. 2023;4:100955 pubmed publisher
	Nicolas A, Sannier G, Dub xe9 M, Nayrac M, Tauzin A, Painter M, et al. An extended SARS-CoV-2 mRNA vaccine prime-boost interval enhances B cell immunity with limited impact on T cells. iScience. 2023;26:105904 pubmed publisher
	Faissner S, Heitmann N, Plaza Sirvent C, Trendelenburg P, Ceylan U, Motte J, et al. Immune response in ofatumumab treated multiple sclerosis patients after SARS-CoV-2 vaccination. Front Immunol. 2022;13:980526 pubmed publisher
	Vadrevu K, Ganneru B, Reddy S, Jogdand H, Raju D, Sapkal G, et al. Persistence of immunity and impact of third dose of inactivated COVID-19 vaccine against emerging variants. Sci Rep. 2022;12:12038 pubmed publisher
	Nayrac M, Dub xe9 M, Sannier G, Nicolas A, Marchitto L, Tastet O, et al. Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen. Cell Rep. 2022;39:111013 pubmed publisher
	Vikkurthi R, Ansari A, Pai A, Jha S, Sachan S, Pandit S, et al. Inactivated whole-virion vaccine BBV152/Covaxin elicits robust cellular immune memory to SARS-CoV-2 and variants of concern. Nat Microbiol. 2022;7:974-985 pubmed publisher
	. A blood atlas of COVID-19 defines hallmarks of disease severity and specificity. Cell. 2022;185:916-938.e58 pubmed publisher
	Tauzin A, Nayrac M, Benlarbi M, Gong S, Gasser R, Beaudoin Bussieres G, et al. A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses. Cell Host Microbe. 2021;29:1137-1150.e6 pubmed publisher
	Stephenson E, Reynolds G, Botting R, Calero Nieto F, Morgan M, Tuong Z, et al. Single-cell multi-omics analysis of the immune response in COVID-19. Nat Med. 2021;27:904-916 pubmed publisher
	Bourges C, Groff A, Burren O, Gerhardinger C, Mattioli K, Hutchinson A, et al. Resolving mechanisms of immune-mediated disease in primary CD4 T cells. EMBO Mol Med. 2020;12:e12112 pubmed publisher
	Yang W, Lee K, Srivastava R, Kuo F, Krishna C, Chowell D, et al. Immunogenic neoantigens derived from gene fusions stimulate T cell responses. Nat Med. 2019;25:767-775 pubmed publisher
	de Jonge K, Ebering A, Nassiri S, Maby El Hajjami H, Ouertatani Sakouhi H, Baumgaertner P, et al. Circulating CD56bright NK cells inversely correlate with survival of melanoma patients. Sci Rep. 2019;9:4487 pubmed publisher

product information

Antigen :

CD137

Apps. Abbrev. :

Cat # :

309826

Clone :

4B4-1

Item :

PE/Dazzle™ 594 anti-human CD137 (4-1BB)

Isotype :

Mouse IgG1, κ

Other Names :

4-1BB, ILA, CD137, TNFRSF9

Size :

100 tests

Price (USD) :

323 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PE_DZL594

Immunogen :

Ectodomain of recombinant human 4-1BB fusion protein

Application Notes :

Additional reported applications (for the relevant formats) include: immunoprecipitation^1,4, inhibition of cytokine production^2,3, and ELISA. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 309804) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by Streptavidin-PE (Cat. No. 405204)).;

more info or order :

BioLegend product webpage