Alexa Fluor® 700 anti-human CD137 (4-1BB) | BioLegend 309816 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 700 anti-human CD137 (4-1BB)

catalog :

309816

quantity :

100 μg

price :

370 USD

clonality :

monoclonal

host :

mouse

conjugate :

AF700

clone name :

4B4-1

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 3a	Pei Y, Xiang Z, Wen K, Tu C, Wang X, Zhang Y, et al. CD137 Costimulation Enhances the Antitumor Activity of Vγ9Vδ2-T Cells in IL-10-Mediated Immunosuppressive Tumor Microenvironment. Front Immunol. 2022;13:872122 pubmed publisher
flow cytometry; human	Chiou S, Tseng D, Reuben A, Mallajosyula V, Molina I, Conley S, et al. Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery. Immunity. 2021;54:586-602.e8 pubmed publisher
flow cytometry; human; 3:50; loading ...; fig 3j	Park J, Botting R, Domínguez Conde C, Popescu D, Lavaert M, Kunz D, et al. A cell atlas of human thymic development defines T cell repertoire formation. Science. 2020;367: pubmed publisher
flow cytometry; human; fig 3g	Montel Hagen A, Seet C, Li S, Chick B, Zhu Y, Chang P, et al. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019;24:376-389.e8 pubmed publisher
flow cytometry; human; loading ...; fig s2b	Scheper W, Kelderman S, Fanchi L, Linnemann C, Bendle G, de Rooij M, et al. Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers. Nat Med. 2019;25:89-94 pubmed publisher
	Gyurdieva A, Zajic S, Chang Y, Houseman E, Zhong S, Kim J, et al. Biomarker correlates with response to NY-ESO-1 TCR T cells in patients with synovial sarcoma. Nat Commun. 2022;13:5296 pubmed publisher
	Trivedi S, Labuz D, Anderson C, Araújo C, Blair A, Middleton E, et al. Mucosal-associated invariant T (MAIT) cells mediate protective host responses in sepsis. elife. 2020;9: pubmed publisher
	Gannon P, Harari A, Auger A, Murgues C, Zangiacomi V, Rubin O, et al. Development of an optimized closed and semi-automatic protocol for Good Manufacturing Practice manufacturing of tumor-infiltrating lymphocytes in a hospital environment. Cytotherapy. 2020;22:780-791 pubmed publisher
	McGinley A, Sutton C, Edwards S, Leane C, Decourcey J, Teijeiro A, et al. Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells. Immunity. 2020;52:342-356.e6 pubmed publisher

product information

Antigen :

CD137

Apps. Abbrev. :

Cat # :

309816

Clone :

4B4-1

Item :

Alexa Fluor® 700 anti-human CD137 (4-1BB)

Isotype :

Mouse IgG1, κ

Other Names :

4-1BB, ILA, CD137, TNFRSF9

Size :

100 μg

Price (USD) :

370 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

A700

Immunogen :

Ectodomain of recombinant human 4-1BB fusion protein

Application Notes :

Additional reported applications (for the relevant formats) include: immunoprecipitation^1,4, inhibition of cytokine production^2,3, and ELISA. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 309804) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by Streptavidin-PE (Cat. No. 405204)).;

more info or order :

BioLegend product webpage