Alexa Fluor® 488 anti-human CD282 (TLR2) | BioLegend 309712 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 488 anti-human CD282 (TLR2)

catalog :

309712

quantity :

100 tests

price :

293 USD

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

TL2.1

reactivity :

human

application :

flow cytometry, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; loading ...; fig 3a	Cheng W, van Asten S, Burns L, Evans H, Walter G, Hashim A, et al. Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses. Eur J Immunol. 2016;46:2211-21 pubmed publisher
	Sureshchandra S, Marshall N, Mendoza N, Jankeel A, Zulu M, Messaoudi I. Functional and genomic adaptations of blood monocytes to pregravid obesity during pregnancy. iScience. 2021;24:102690 pubmed publisher
	Pham T, Meziane O, Miah M, Volodina O, Colas C, Beland K, et al. Flt3L-Mediated Expansion of Plasmacytoid Dendritic Cells Suppresses HIV Infection in Humanized Mice. Cell Rep. 2019;29:2770-2782.e5 pubmed publisher
	Elass Rochard E, Rombouts Y, Coddeville B, Maes E, Blervaque R, Hot D, et al. Structural determination and Toll-like receptor 2-dependent proinflammatory activity of dimycolyl-diarabino-glycerol from Mycobacterium marinum. J Biol Chem. 2012;287:34432-44 pubmed publisher
	Harris K. Monocytes differentiated with GM-CSF and IL-15 initiate Th17 and Th1 responses that are contact-dependent and mediated by IL-15. J Leukoc Biol. 2011;90:727-34 pubmed publisher
	Weiss D, Souza C, Evanson O, Sanders M, Rutherford M. Bovine monocyte TLR2 receptors differentially regulate the intracellular fate of Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium. J Leukoc Biol. 2008;83:48-55 pubmed
	Goo S, Han Y, Kim W, Lee K, Park S. Vibrio vulnificus IlpA-induced cytokine production is mediated by Toll-like receptor 2. J Biol Chem. 2007;282:27647-58 pubmed
	Chavakis E, Hain A, Vinci M, Carmona G, Bianchi M, Vajkoczy P, et al. High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Circ Res. 2007;100:204-12 pubmed

product information

Antigen :

CD282

Apps. Abbrev. :

Cat # :

309712

Clone :

TL2.1

Item :

Alexa Fluor® 488 anti-human CD282 (TLR2)

Isotype :

Mouse IgG2a, κ

Other Names :

Toll like receptor 2, TIL4, CD282

Size :

100 tests

Price (USD) :

293 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

A488

Immunogen :

Human TLR2-transfected CHO cells

Application Notes :

The TL2.1 antibody is useful for blocking studies. It has been reported to block TLR2 agonist-induced cellular activation. Additional reported applications (for the relevant formats) include: inhibition of PGP activity and blocking of cytokine production^1,3,7, immunoprecipitation^1, immunohistochemistry of 4% paraformaldehyde-fixed frozen sections^2 and immunohistochemistry of HOPE-fixed (HEPES-glutamic acid buffer-mediated organic solvent protection effect) paraffin-embedded sections^4 , and Western blotting^2. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 309716) (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered).;

more info or order :

BioLegend product webpage