product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human CD282 (TLR2)
catalog :
309707
quantity :
25 tests
price :
141 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
TL2.1
reactivity :
human
application :
flow cytometry
more info or order :
citations: 7
Reference
Ufimtseva E, Eremeeva N, Umpeleva T, Vakhrusheva D, Skornyakov S. Mycobacterium tuberculosis Load in Host Cells and the Antibacterial Activity of Alveolar Macrophages Are Linked and Differentially Regulated in Various Lung Lesions of Patients with Pulmonary Tuberculosis. Int J Mol Sci. 2021;22: pubmed publisher
Aguilar Briseño J, Upasani V, Ellen B, Moser J, Pauzuolis M, Ruiz Silva M, et al. TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis. Nat Commun. 2020;11:3177 pubmed publisher
OhAinle M, Helms L, Vermeire J, Roesch F, Humes D, Basom R, et al. A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV. elife. 2018;7: pubmed publisher
Raffray L, Giry C, Vandroux D, Kuli B, Randrianjohany A, Péquin A, et al. Major Neutrophilia Observed in Acute Phase of Human Leptospirosis Is Not Associated with Increased Expression of Granulocyte Cell Activation Markers. PLoS ONE. 2016;11:e0165716 pubmed publisher
Glaser K, Fehrholz M, Curstedt T, Kunzmann S, Speer C. Effects of the New Generation Synthetic Reconstituted Surfactant CHF5633 on Pro- and Anti-Inflammatory Cytokine Expression in Native and LPS-Stimulated Adult CD14+ Monocytes. PLoS ONE. 2016;11:e0146898 pubmed publisher
Magalhães L, Viana A, Chiari E, Galvão L, Gollob K, Dutra W. Differential Activation of Human Monocytes and Lymphocytes by Distinct Strains of Trypanosoma cruzi. PLoS Negl Trop Dis. 2015;9:e0003816 pubmed publisher
Fiala M, Liu P, Espinosa Jeffrey A, Rosenthal M, Bernard G, Ringman J, et al. Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin. Proc Natl Acad Sci U S A. 2007;104:12849-54 pubmed
product information
Antigen :
CD282
Apps. Abbrev. :
FC
Cat # :
309707
Clone :
TL2.1
Item :
PE anti-human CD282 (TLR2)
Isotype :
Mouse IgG2a, κ
Other Names :
Toll like receptor 2, TIL4, CD282
Size :
25 tests
Price (USD) :
141 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Immunogen :
Human TLR2-transfected CHO cells
Application Notes :
The TL2.1 antibody is useful for blocking studies. It has been reported to block TLR2 agonist-induced cellular activation. Additional reported applications (for the relevant formats) include: inhibition of PGP activity and blocking of cytokine production^1,3,7, immunoprecipitation^1, immunohistochemistry of 4% paraformaldehyde-fixed frozen sections^2 and immunohistochemistry of HOPE-fixed (HEPES-glutamic acid buffer-mediated organic solvent protection effect) paraffin-embedded sections^4 , and Western blotting^2. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 309716) (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA