Purified anti-human CD282 (TLR2) | BioLegend 309702 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-human CD282 (TLR2)

catalog :

309702

quantity :

100 μg

price :

258 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TL2.1

reactivity :

human

application :

western blot, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1a	Hally K, La Flamme A, Larsen P, Harding S. Platelet Toll-like receptor (TLR) expression and TLR-mediated platelet activation in acute myocardial infarction. Thromb Res. 2017;158:8-15 pubmed publisher
blocking or activating experiments; human; loading ...; fig 3a	Cheng W, van Asten S, Burns L, Evans H, Walter G, Hashim A, et al. Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses. Eur J Immunol. 2016;46:2211-21 pubmed publisher
	Tseng Y, Chang C, Chang Y. Novel Virulence Role of Pneumococcal NanA in Host Inflammation and Cell Death Through the Activation of Inflammasome and the Caspase Pathway. Front Cell Infect Microbiol. 2021;11:613195 pubmed publisher
	Park H, Lim S, Hwang J, Zhang W, You S, Jin J. Cancer immunotherapy using a polysaccharide from Codium fragile in a murine model. Oncoimmunology. 2020;9:1772663 pubmed publisher
	Manukyan G, Papajik T, Gajdos P, Mikulkova Z, Urbanová R, Gabcova G, et al. Neutrophils in chronic lymphocytic leukemia are permanently activated and have functional defects. Oncotarget. 2017;8:84889-84901 pubmed publisher
	Wang Z, Mascarenhas N, Eckmann L, Miyamoto Y, Sun X, Kawakami T, et al. Skin microbiome promotes mast cell maturation by triggering stem cell factor production in keratinocytes. J Allergy Clin Immunol. 2017;139:1205-1216.e6 pubmed publisher
	Elass Rochard E, Rombouts Y, Coddeville B, Maes E, Blervaque R, Hot D, et al. Structural determination and Toll-like receptor 2-dependent proinflammatory activity of dimycolyl-diarabino-glycerol from Mycobacterium marinum. J Biol Chem. 2012;287:34432-44 pubmed publisher
	Harris K. Monocytes differentiated with GM-CSF and IL-15 initiate Th17 and Th1 responses that are contact-dependent and mediated by IL-15. J Leukoc Biol. 2011;90:727-34 pubmed publisher
	Weiss D, Souza C, Evanson O, Sanders M, Rutherford M. Bovine monocyte TLR2 receptors differentially regulate the intracellular fate of Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium. J Leukoc Biol. 2008;83:48-55 pubmed
	Goo S, Han Y, Kim W, Lee K, Park S. Vibrio vulnificus IlpA-induced cytokine production is mediated by Toll-like receptor 2. J Biol Chem. 2007;282:27647-58 pubmed
	Chavakis E, Hain A, Vinci M, Carmona G, Bianchi M, Vajkoczy P, et al. High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Circ Res. 2007;100:204-12 pubmed
	Poupot M, Griffe L, Marchand P, Maraval A, Rolland O, Martinet L, et al. Design of phosphorylated dendritic architectures to promote human monocyte activation. FASEB J. 2006;20:2339-51 pubmed

product information

Antigen :

CD282

Apps. Abbrev. :

FC, Block, IHC-P, IHC-F, IP, WB

Cat # :

309702

Clone :

TL2.1

Item :

Purified anti-human CD282 (TLR2)

Isotype :

Mouse IgG2a, κ

Other Names :

Toll like receptor 2, TIL4, CD282

Size :

100 μg

Price (USD) :

258 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

Human TLR2-transfected CHO cells

Application Notes :

The TL2.1 antibody is useful for blocking studies. It has been reported to block TLR2 agonist-induced cellular activation. Additional reported applications (for the relevant formats) include: inhibition of PGP activity and blocking of cytokine production^1,3,7, immunoprecipitation^1, immunohistochemistry of 4% paraformaldehyde-fixed frozen sections^2 and immunohistochemistry of HOPE-fixed (HEPES-glutamic acid buffer-mediated organic solvent protection effect) paraffin-embedded sections^4 , and Western blotting^2. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 309716) (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered).;

more info or order :

BioLegend product webpage