LEAF™ Purified anti-human CD210 (IL-10 R) | BioLegend 308805 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

LEAF™ Purified anti-human CD210 (IL-10 R)

catalog :

308805

quantity :

50 μg

price :

120 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

3F9

reactivity :

human, Rhesus monkey

application :

neutralization, immunoprecipitation, flow cytometry

citations: 3

Reference
Joffe M, Necula A, Chand R, McWhinney B, Krishnamurthy B, Loudovaris T, et al. Residual methylprednisolone suppresses human T-cell responses to spleen, but not islet, extracts from deceased organ donors. Int Immunol. 2012;24:447-53 pubmed publisher
Liu B, Groothuismink Z, Janssen H, Boonstra A. Role for IL-10 in inducing functional impairment of monocytes upon TLR4 ligation in patients with chronic HCV infections. J Leukoc Biol. 2011;89:981-8 pubmed publisher
Huang Y, Zozulya A, Weidenfeller C, Schwab N, Wiendl H. T cell suppression by naturally occurring HLA-G-expressing regulatory CD4+ T cells is IL-10-dependent and reversible. J Leukoc Biol. 2009;86:273-81 pubmed publisher

product information

Antigen :

CD210 (IL-10 R)

Apps. Abbrev. :

Flow Cytometry, Block, IP

Cat # :

308805

Clone :

3F9

Item :

LEAF™ Purified anti-human CD210 (IL-10 R)

Isotype :

Rat IgG2a, κ

Other Names :

IL-10 Receptor, IL-10R

Size :

50 μg

Price (USD) :

120 USD

Reactivity :

Human, African Green, Baboon, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

LEAF

Immunogen :

shIL-10R

Application Notes :

Clone 3F9 recognizes the IL-10-binding epitope of IL-10R1. 8 Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , in vitro blocking 1-3 of human IL-10 binding to IL-10R. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 308804) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated anti-rat IgG second step (Cat. No. 405402), followed by SAv-PE (Cat. No. 405204). The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 308806). For highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 308810) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).