product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human IFN-γ R β chain
catalog :
308504
quantity :
100 tests
price :
304 USD
clonality :
monoclonal
host :
hamsters
conjugate :
PE
clone name :
2HUB-159
reactivity :
African green monkey, human, mouse
application :
flow cytometry
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:100; fig 4c
Arenas E, Martínez Sabadell A, Rius Ruiz I, Román Alonso M, Escorihuela M, Luque A, et al. Acquired cancer cell resistance to T cell bispecific antibodies and CAR T targeting HER2 through JAK2 down-modulation. Nat Commun. 2021;12:1237 pubmed publisher
  • flow cytometry; African green monkey; fig 3a
Ouwendijk W, van Veen S, Mahalingam R, Verjans G. Simian varicella virus inhibits the interferon gamma signalling pathway. J Gen Virol. 2017;: pubmed publisher
Mart xed nez Sabadell A, Morancho B, Rius Ruiz I, Rom xe1 n Alonso M, Ovejero Romero P, Escorihuela M, et al. The target antigen determines the mechanism of acquired resistance to T cell-based therapies. Cell Rep. 2022;41:111430 pubmed publisher
Kenty J, Pelayo G, Leite N. Retrieval and purification of human β cells from stem cell-derived islet engrafted mice. STAR Protoc. 2021;2:100675 pubmed publisher
Lu Y, Zhao Q, Liao J, Song E, Xia Q, Pan J, et al. Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity. Cell. 2020;180:1081-1097.e24 pubmed publisher
Ferrando Martinez S, Moysi E, Pegu A, Andrews S, Nganou Makamdop K, Ambrozak D, et al. Accumulation of follicular CD8+ T cells in pathogenic SIV infection. J Clin Invest. 2018;128:2089-2103 pubmed publisher
Kulling P, Olson K, Hamele C, Toro M, Tan S, Feith D, et al. Dysregulation of the IFN-?-STAT1 signaling pathway in a cell line model of large granular lymphocyte leukemia. PLoS ONE. 2018;13:e0193429 pubmed publisher
Dela Peña Ponce M, Rodriguez Nieves J, Bernhardt J, Tuck R, Choudhary N, Mengual M, et al. Increasing JAK/STAT Signaling Function of Infant CD4+ T Cells during the First Year of Life. Front Pediatr. 2017;5:15 pubmed publisher
Tjon A, van Gent R, Jaadar H, Martin van Hagen P, Mancham S, van der Laan L, et al. Intravenous immunoglobulin treatment in humans suppresses dendritic cell function via stimulation of IL-4 and IL-13 production. J Immunol. 2014;192:5625-34 pubmed publisher
product information
Antigen :
IFN-gamma R beta chain
Apps. Abbrev. :
FC
Cat # :
308504
Clone :
2HUB-159
Item :
PE anti-human IFN-γ R β chain
Isotype :
Hamster IgG
Other Names :
IFN-γRβ, IFNγAF-1
Size :
100 tests
Price (USD) :
304 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Hamster
Conjugate/Tag/Label :
PE
Immunogen :
soluable extracellular domains of the human IFN-γ R β chain
Application Notes :
Additional reported applications (for the relevant formats) include: Western blotting^2,3 and immunoprecipitation^2,3. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 308504) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated anti-Armenian hamster IgG second step (Cat. No. 405501), followed by SAv-PE (Cat. No. 405204)). TThe LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 308506).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA