APC anti-human CD253 (TRAIL) | BioLegend 308209 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human CD253 (TRAIL)

catalog :

308209

quantity :

25 tests

price :

125 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

RIK-2

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 5

Reference
Di Benedetto C, Khan T, Serrano Saenz S, Rodriguez Lemus A, Klomsiri C, Beutel T, et al. Enhancer Clusters Drive Type I Interferon-Induced TRAIL Overexpression in Cancer, and Its Intracellular Protein Accumulation Fails to Induce Apoptosis. Cancers (Basel). 2023;15: pubmed publisher
Chulpanova D, Pukhalskaia T, Gilazieva Z, Filina Y, Mansurova M, Rizvanov A, et al. Cytochalasin B-Induced Membrane Vesicles from TRAIL-Overexpressing Mesenchymal Stem Cells Induce Extrinsic Pathway of Apoptosis in Breast Cancer Mouse Model. Curr Issues Mol Biol. 2023;45:571-592 pubmed publisher
Van der Meer J, de Jonge P, van der Waart A, Geerlings A, Moonen J, Brummelman J, et al. CD34+ progenitor-derived NK cell and gemcitabine combination therapy increases killing of ovarian cancer cells in NOD/SCID/IL2Rgnull mice. Oncoimmunology. 2021;10:1981049 pubmed publisher
Schwartz J, Zhang H, Ende Z, Deymier M, Lee T, Singer J, et al. Characterization of the Plasmacytoid Dendritic Cell Response to Transmitted/Founder and Nontransmitted Variants of HIV-1. J Virol. 2018;92: pubmed publisher
Roybal K, Williams J, Morsut L, Rupp L, Kolinko I, Choe J, et al. Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors. Cell. 2016;167:419-432.e16 pubmed publisher

product information

Antigen :

CD253

Apps. Abbrev. :

Cat # :

308209

Clone :

RIK-2

Item :

APC anti-human CD253 (TRAIL)

Isotype :

Mouse IgG1, κ

Other Names :

Apo-2 ligand, Apo-2L, TNFSF10, CD253

Size :

25 tests

Price (USD) :

125 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC

Immunogen :

Human TRAIL-transfected mouse cell line

Application Notes :

Additional reported applications (for the relevant formats) include: blocking^1-4 of TRAIL-induced apoptosis and T cell mediated cytotoxicity. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 308214).;

more info or order :

BioLegend product webpage