Purified anti-human CD253 (Trail) | BioLegend 308202 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-human CD253 (Trail)

catalog :

308202

quantity :

100 μg

price :

126 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

RIK-2

reactivity :

human

application :

immunocytochemistry, neutralization, flow cytometry, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:50; loading ...; fig 4d	Smith N, Pietrancosta N, Davidson S, Dutrieux J, Chauveau L, Cutolo P, et al. Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement. Nat Commun. 2017;8:14253 pubmed publisher
blocking or activating experiments; human; fig 4	Difranco K, Johnson Farley N, Bertino J, Elson D, Vega B, Belinka B, et al. LFA-1-targeting Leukotoxin (LtxA; LeukotheraÂ®) causes lymphoma tumor regression in a humanized mouse model and requires caspase-8 and Fas to kill malignant lymphocytes. Leuk Res. 2015;39:649-56 pubmed publisher
	Lu Y, Zhao Q, Liao J, Song E, Xia Q, Pan J, et al. Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity. Cell. 2020;180:1081-1097.e24 pubmed publisher
	Carlsten M, Namazi A, Reger R, Levy E, Berg M, St Hilaire C, et al. Bortezomib sensitizes multiple myeloma to NK cells via ER-stress-induced suppression of HLA-E and upregulation of DR5. Oncoimmunology. 2019;8:e1534664 pubmed publisher
	Henrich I, Young R, Quick L, Oliveira A, Chou M. USP6 Confers Sensitivity to IFN-Mediated Apoptosis through Modulation of TRAIL Signaling in Ewing Sarcoma. Mol Cancer Res. 2018;16:1834-1843 pubmed publisher
	Kemter E, Lieke T, Kessler B, Kurome M, Wuensch A, Summerfield A, et al. Human TNF-related apoptosis-inducing ligand-expressing dendritic cells from transgenic pigs attenuate human xenogeneic T cell responses. Xenotransplantation. 2012;19:40-51 pubmed publisher

product information

Antigen :

CD253

Apps. Abbrev. :

FC, Block

Cat # :

308202

Clone :

RIK-2

Item :

Purified anti-human CD253 (Trail)

Isotype :

Mouse IgG1, κ

Other Names :

Apo-2 ligand, Apo-2L, TNFSF10, CD253

Size :

100 μg

Price (USD) :

126 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

Human TRAIL-transfected mouse cell line

Application Notes :

Additional reported applications (for the relevant formats) include: blocking^1-4 of TRAIL-induced apoptosis and T cell mediated cytotoxicity. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 308214).;

more info or order :

BioLegend product webpage