PE/Dazzle™ 594 anti-human Perforin | BioLegend 308132 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Dazzle™ 594 anti-human Perforin

catalog :

308132

quantity :

100 tests

price :

370 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

dG9

reactivity :

human

application :

immunocytochemistry, flow cytometry

more info or order :

BioLegend product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 2a	Ingegnere T, Mariotti F, Pelosi A, Quintarelli C, De Angelis B, Tumino N, et al. Human CAR NK Cells: A New Non-viral Method Allowing High Efficient Transfection and Strong Tumor Cell Killing. Front Immunol. 2019;10:957 pubmed publisher
	Gong Y, Shao H, Li Y, Brafford P, Stine Z, Sun J, et al. Na+/H+-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells. Cancer Res Commun. 2022;2:842-856 pubmed publisher
	Shen Z, Patel M, Rodríguez García M, Wira C. Aging beyond menopause selectively decreases CD8+ T cell numbers but enhances cytotoxic activity in the human endometrium. Immun Ageing. 2022;19:55 pubmed publisher
	Pathania A, Prathipati P, Olwenyi O, Chava S, Smith O, Gupta S, et al. miR-15a and miR-15b modulate natural killer and CD8+T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma. Mol Ther Oncolytics. 2022;25:308-329 pubmed publisher
	McGinley A, Sutton C, Edwards S, Leane C, Decourcey J, Teijeiro A, et al. Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells. Immunity. 2020;52:342-356.e6 pubmed publisher
	Wood S, Meeths M, Chiang S, Bechensteen A, Boelens J, Heilmann C, et al. Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. Blood. 2009;114:4117-27 pubmed publisher

product information

Antigen :

Perforin

Apps. Abbrev. :

ICFC

Cat # :

308132

Clone :

dG9

Item :

PE/Dazzle™ 594 anti-human Perforin

Isotype :

Mouse IgG2b, κ

Other Names :

PRF1, P1, PFP, HPLH2

Size :

100 tests

Price (USD) :

370 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PE_DZL594

Immunogen :

Purified granules from the human lymphoma cell line

Application Notes :

Clone dG9 primarily recognizes perforin associated with cytotoxic granules^9. Additional reported applications (for the relevant formats) include: immunoprecipitation, intracellular flow cytometric analysis and immunofluorescence microscopy^5,7, and immunohistochemical staining of acetone-fixed frozen tissue sections and formalin-fixed paraffin-embedded tissue sections^1,4.;Does not cross-react with mouse^1.;

more info or order :

BioLegend product webpage