Pacific Blue™ anti-human Perforin | BioLegend 308118 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Pacific Blue™ anti-human Perforin

catalog :

308118

quantity :

100 tests

price :

311 USD

clonality :

monoclonal

host :

mouse

conjugate :

Pacific Blue

clone name :

dG9

reactivity :

human

application :

immunocytochemistry, flow cytometry

more info or order :

BioLegend product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 7a-7b	Bhattacharya P, Ellegård R, Khalid M, Svanberg C, Govender M, Keita A, et al. Complement opsonization of HIV affects primary infection of human colorectal mucosa and subsequent activation of T cells. elife. 2020;9: pubmed publisher
	Schmitz T, Hoffmann V, Olliges E, Bobinger A, Popovici R, Nößner E, et al. Reduced frequency of perforin-positive CD8+ T cells in menstrual effluent of endometriosis patients. J Reprod Immunol. 2021;148:103424 pubmed publisher
	Crespo A, Mulik S, Dotiwala F, Ansara J, Sen Santara S, Ingersoll K, et al. Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts. Cell. 2020;182:1125-1139.e18 pubmed publisher
	Shah S, Manickam C, Ram D, Kroll K, Itell H, Permar S, et al. CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques. Cell Rep. 2018;25:2766-2774.e3 pubmed publisher
	Manickam C, Rajakumar P, Wachtman L, Kramer J, Martinot A, Varner V, et al. Acute Liver Damage Associated with Innate Immune Activation in a Small Nonhuman Primate Model of Hepacivirus Infection. J Virol. 2016;90:9153-62 pubmed publisher
	Kim P, Kwilas A, Xu W, Alter S, Jeng E, Wong H, et al. IL-15 superagonist/IL-15RÎ±Sushi-Fc fusion complex (IL-15SA/IL-15RÎ±Su-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-tumor activity against murine breast and colon carcinomas. Oncotarget. 2016;7:16130-45 pubmed publisher
	Wood S, Meeths M, Chiang S, Bechensteen A, Boelens J, Heilmann C, et al. Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. Blood. 2009;114:4117-27 pubmed publisher

product information

Antigen :

Perforin

Apps. Abbrev. :

ICFC

Cat # :

308118

Clone :

dG9

Item :

Pacific Blue™ anti-human Perforin

Isotype :

Mouse IgG2b, κ

Other Names :

PRF1, P1, PFP, HPLH2

Size :

100 tests

Price (USD) :

311 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Immunogen :

Purified granules from the human lymphoma cell line

Application Notes :

Clone dG9 primarily recognizes perforin associated with cytotoxic granules^9. Additional reported applications (for the relevant formats) include: immunoprecipitation, intracellular flow cytometric analysis and immunofluorescence microscopy^5,7, and immunohistochemical staining of acetone-fixed frozen tissue sections and formalin-fixed paraffin-embedded tissue sections^1,4.;Does not cross-react with mouse^1.;

more info or order :

BioLegend product webpage