| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry; mouse; loading ...; fig 2a
| Chitirala P, Chang H, Martzloff P, Harenberg C, Ravichandran K, Abdulreda M, et al. Studying the biology of cytotoxic T lymphocytes in vivo with a fluorescent granzyme B-mTFP knock-in mouse. elife. 2020;9: pubmed publisher |
- flow cytometry; human; 1:50; loading ...; fig 2b
- immunocytochemistry; human; loading ...; fig 2a
| Zurli V, Montecchi T, Heilig R, Poschke I, Volkmar M, Wimmer G, et al. Phosphoproteomics of CD2 signaling reveals AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells. Sci Signal. 2020;13: pubmed publisher |
- flow cytometry; human; loading ...; fig 2a
| Ingegnere T, Mariotti F, Pelosi A, Quintarelli C, De Angelis B, Tumino N, et al. Human CAR NK Cells: A New Non-viral Method Allowing High Efficient Transfection and Strong Tumor Cell Killing. Front Immunol. 2019;10:957 pubmed publisher |
- flow cytometry; human; loading ...; fig 1j
| Ye W, Chew M, Hou J, Lai F, Leopold S, Loo H, et al. Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway. PLoS Pathog. 2018;14:e1007298 pubmed publisher |
- other; human; loading ...; fig 1b
| Srpan K, Ambrose A, Karampatzakis A, Saeed M, Cartwright A, Guldevall K, et al. Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells. J Cell Biol. 2018;217:3267-3283 pubmed publisher |
- flow cytometry; human; 5 ug/ml; fig 5
| Khazen R, Müller S, Gaudenzio N, Espinosa E, Puissegur M, Valitutti S. Melanoma cell lysosome secretory burst neutralizes the CTL-mediated cytotoxicity at the lytic synapse. Nat Commun. 2016;7:10823 pubmed publisher |
| Gong Y, Shao H, Li Y, Brafford P, Stine Z, Sun J, et al. Na+/H+-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells. Cancer Res Commun. 2022;2:842-856 pubmed publisher |
| Li Y, Yu M, Yin J, Yan H, Wang X. Enhanced Calcium Signal Induces NK Cell Degranulation but Inhibits Its Cytotoxic Activity. J Immunol. 2022;208:347-357 pubmed publisher |
| Kim N, Yi E, Kwon S, Park H, Kwon H, Kim H. Filamin A Is Required for NK Cell Cytotoxicity at the Expense of Cytokine Production via Synaptic Filamentous Actin Modulation. Front Immunol. 2021;12:792334 pubmed publisher |
| German Y, Vulliard L, Kamnev A, Pfajfer L, Huemer J, Mautner A, et al. Morphological profiling of human T and NK lymphocytes by high-content cell imaging. Cell Rep. 2021;36:109318 pubmed publisher |
| Bezverbnaya K, Moogk D, Cummings D, Baker C, Aarts C, Denisova G, et al. Development of a B-cell maturation antigen-specific T-cell antigen coupler receptor for multiple myeloma. Cytotherapy. 2021;23:820-832 pubmed publisher |
| Thieme C, Anft M, Paniskaki K, Blazquez Navarro A, Doevelaar A, Seibert F, et al. Robust T Cell Response Toward Spike, Membrane, and Nucleocapsid SARS-CoV-2 Proteins Is Not Associated with Recovery in Critical COVID-19 Patients. Cell Rep Med. 2020;1:100092 pubmed publisher |
| Xie C, Jiang B, Qin L, Tellides G, Kirkiles Smith N, Jane Wit D, et al. Complement-activated interferon-γ-primed human endothelium transpresents interleukin-15 to CD8+ T cells. J Clin Invest. 2020;130:3437-3452 pubmed publisher |
| Monel B, McKeon A, Lamothe Molina P, Jani P, Boucau J, Pacheco Y, et al. HIV Controllers Exhibit Effective CD8+ T Cell Recognition of HIV-1-Infected Non-activated CD4+ T Cells. Cell Rep. 2019;27:142-153.e4 pubmed publisher |
| Sevilya Z, Chorin E, Gal Garber O, Zelinger E, Turner D, Avidor B, et al. Killing of Latently HIV-Infected CD4 T Cells by Autologous CD8 T Cells Is Modulated by Nef. Front Immunol. 2018;9:2068 pubmed publisher |
| Kim N, Choi J, Park H, Kim I, Kim H. Amphotericin B, an Anti-Fungal Medication, Directly Increases the Cytotoxicity of NK Cells. Int J Mol Sci. 2017;18: pubmed publisher |
| Salzer E, Cağdaş D, Hons M, Mace E, Garncarz W, Petronczki Ö, et al. RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics. Nat Immunol. 2016;17:1352-1360 pubmed publisher |
| Mace E, Orange J. Lytic immune synapse function requires filamentous actin deconstruction by Coronin 1A. Proc Natl Acad Sci U S A. 2014;111:6708-13 pubmed publisher |
| Pérez Quintero L, Roncagalli R, Guo H, Latour S, Davidson D, Veillette A. EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase C?, Ca++, and Erk, leading to granule polarization. J Exp Med. 2014;211:727-42 pubmed publisher |
| Peruzzi G, Femnou L, Gil Krzewska A, Borrego F, Weck J, Krzewski K, et al. Membrane-type 6 matrix metalloproteinase regulates the activation-induced downmodulation of CD16 in human primary NK cells. J Immunol. 2013;191:1883-94 pubmed publisher |
| Sanchez Ruiz Y, Valitutti S, Dupré L. Stepwise maturation of lytic granules during differentiation and activation of human CD8+ T lymphocytes. PLoS ONE. 2011;6:e27057 pubmed publisher |
| Rak G, Mace E, Banerjee P, Svitkina T, Orange J. Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse. PLoS Biol. 2011;9:e1001151 pubmed publisher |
| Qu B, Pattu V, Junker C, Schwarz E, Bhat S, Kummerow C, et al. Docking of lytic granules at the immunological synapse in human CTL requires Vti1b-dependent pairing with CD3 endosomes. J Immunol. 2011;186:6894-904 pubmed publisher |
| Wood S, Meeths M, Chiang S, Bechensteen A, Boelens J, Heilmann C, et al. Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. Blood. 2009;114:4117-27 pubmed publisher |
| Dutertre C, Bonnin Gélizé E, Pulford K, Bourel D, Fridman W, Teillaud J. A novel subset of NK cells expressing high levels of inhibitory FcgammaRIIB modulating antibody-dependent function. J Leukoc Biol. 2008;84:1511-20 pubmed publisher |
| Krzewski K, Chen X, Strominger J. WIP is essential for lytic granule polarization and NK cell cytotoxicity. Proc Natl Acad Sci U S A. 2008;105:2568-73 pubmed publisher |
| Bryceson Y, Rudd E, Zheng C, Edner J, Ma D, Wood S, et al. Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients. Blood. 2007;110:1906-15 pubmed |
