FITC anti-human Perforin | BioLegend 308104 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

FITC anti-human Perforin

catalog :

308104

quantity :

100 tests

price :

258 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

dG9

reactivity :

human

application :

immunocytochemistry

more info or order :

BioLegend product webpage

citations: 8

Reference
Macedo A, Levinger C, Nguyen B, Richard J, Gupta M, Cruz C, et al. The HIV Latency Reversal Agent HODHBt Enhances NK Cell Effector and Memory-Like Functions by Increasing Interleukin-15-Mediated STAT Activation. J Virol. 2022;96:e0037222 pubmed publisher
Leem G, Cheon S, Lee H, Choi S, Jeong S, Kim E, et al. Abnormality in the NK-cell population is prolonged in severe COVID-19 patients. J Allergy Clin Immunol. 2021;148:996-1006.e18 pubmed publisher
de Jonge K, Ebering A, Nassiri S, Maby El Hajjami H, Ouertatani Sakouhi H, Baumgaertner P, et al. Circulating CD56bright NK cells inversely correlate with survival of melanoma patients. Sci Rep. 2019;9:4487 pubmed publisher
Petri R, Hackel A, Hahnel K, Dumitru C, Bruderek K, Flohé S, et al. Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative Function. Stem Cell Reports. 2017;9:985-998 pubmed publisher
Lünemann A, Vanoaica L, Azzi T, Nadal D, MUNZ C. A distinct subpopulation of human NK cells restricts B cell transformation by EBV. J Immunol. 2013;191:4989-95 pubmed publisher
Chen Y, Kuo M, Cheng P, Hsaio H, Lee P, Lin S. Regulation of CD28 expression on umbilical cord blood and adult peripheral blood CD8+ T cells by interleukin(IL)-15/IL-21. Cytokine. 2012;58:40-6 pubmed publisher
Cellerai C, Harari A, Stauss H, Yerly S, Geretti A, Carroll A, et al. Early and prolonged antiretroviral therapy is associated with an HIV-1-specific T-cell profile comparable to that of long-term non-progressors. PLoS ONE. 2011;6:e18164 pubmed publisher
Strauss L, Czystowska M, Szajnik M, Mandapathil M, Whiteside T. Differential responses of human regulatory T cells (Treg) and effector T cells to rapamycin. PLoS ONE. 2009;4:e5994 pubmed publisher

product information

Antigen :

Perforin

Apps. Abbrev. :

ICFC

Cat # :

308104

Clone :

dG9

Item :

FITC anti-human Perforin

Isotype :

Mouse IgG2b, κ

Other Names :

PRF1, P1, PFP, HPLH2

Size :

100 tests

Price (USD) :

258 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

FITC

Immunogen :

Purified granules from the human lymphoma cell line

Application Notes :

Clone dG9 primarily recognizes perforin associated with cytotoxic granules^9. Additional reported applications (for the relevant formats) include: immunoprecipitation, intracellular flow cytometric analysis and immunofluorescence microscopy^5,7, and immunohistochemical staining of acetone-fixed frozen tissue sections and formalin-fixed paraffin-embedded tissue sections^1,4.;Does not cross-react with mouse^1.;

more info or order :

BioLegend product webpage