PerCP anti-human HLA-DR | BioLegend 307627 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PerCP anti-human HLA-DR

catalog :

307627

quantity :

25 tests

price :

143 USD

clonality :

monoclonal

host :

mouse

conjugate :

PerCP

clone name :

L243

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 23

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 8a	Saliba D, Céspedes Donoso P, Balint S, Compeer E, Korobchevskaya K, Valvo S, et al. Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells. elife. 2019;8: pubmed publisher
flow cytometry; rhesus macaque; loading ...; fig 7a	Kasturi S, Kozlowski P, Nakaya H, Burger M, Russo P, Pham M, et al. Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques. J Virol. 2017;91: pubmed publisher
flow cytometry; human	Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
	Georgakis S, Gkirtzimanaki K, Papadaki G, Gakiopoulou H, Drakos E, Eloranta M, et al. NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE. JCI Insight. 2021;6: pubmed publisher
	Akoumianaki T, Vaporidi K, Diamantaki E, Pène F, Beau R, Gresnigt M, et al. Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis. Cell Host Microbe. 2021;29:1277-1293.e6 pubmed publisher
	Koh W, Zayats R, López P, Murooka T. Visualizing Cellular Dynamics and Protein Localization in 3D Collagen. STAR Protoc. 2020;1:100203 pubmed publisher
	Aliu B, Demeestere D, Seydoux E, Boucraut J, Delmont E, Brodovitch A, et al. Selective inhibition of anti-MAG IgM autoantibody binding to myelin by an antigen-specific glycopolymer. J Neurochem. 2020;154:486-501 pubmed publisher
	Eriksson E, Milenova I, Wenthe J, Moreno R, Alemany R, Loskog A. IL-6 Signaling Blockade during CD40-Mediated Immune Activation Favors Antitumor Factors by Reducing TGF-β, Collagen Type I, and PD-L1/PD-1. J Immunol. 2019;: pubmed publisher
	Saito H, Kitagawa K, Yoneda T, Fukui Y, Fujsawa M, Bautista D, et al. Combination of p53-DC vaccine and rAd-p53 gene therapy induced CTLs cytotoxic against p53-deleted human prostate cancer cells in vitro. Cancer Gene Ther. 2017;24:289-296 pubmed publisher
	Venturini J, Cavalcante R, Moris D, Golim M, Levorato A, Reis K, et al. Altered distribution of peripheral blood dendritic cell subsets in patients with pulmonary paracoccidioidomycosis. Acta Trop. 2017;173:185-190 pubmed publisher
	Patel V, Williams H, Li S, Fletcher J, Medbury H. Monocyte inflammatory profile is specific for individuals and associated with altered blood lipid levels. Atherosclerosis. 2017;263:15-23 pubmed publisher
	Woodberry T, Loughland J, Minigo G, Burel J, Amante F, Piera K, et al. Early Immune Regulatory Changes in a Primary Controlled Human Plasmodium vivax Infection: CD1c+ Myeloid Dendritic Cell Maturation Arrest, Induction of the Kynurenine Pathway, and Regulatory T Cell Activation. Infect Immun. 2017;85: pubmed publisher
	Eriksson E, Moreno R, Milenova I, Liljenfeldt L, Dieterich L, Christiansson L, et al. Activation of myeloid and endothelial cells by CD40L gene therapy supports T-cell expansion and migration into the tumor microenvironment. Gene Ther. 2017;24:92-103 pubmed publisher
	Xing Y, Cao R, Hu H. TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles). Cell Death Dis. 2016;7:e2322 pubmed publisher
	Malinarich F, Duan K, Hamid R, Bijin A, Lin W, Poidinger M, et al. High mitochondrial respiration and glycolytic capacity represent a metabolic phenotype of human tolerogenic dendritic cells. J Immunol. 2015;194:5174-86 pubmed publisher
	Santos A, Douiri A, Becares N, Wu S, Stephens A, Radulovic S, et al. Basophil activation test discriminates between allergy and tolerance in peanut-sensitized children. J Allergy Clin Immunol. 2014;134:645-52 pubmed publisher
	Orlov M, Vaida F, Williamson K, Deng Q, Smith D, Duffy P, et al. Antigen-presenting phagocytic cells ingest malaria parasites and increase HIV replication in a tumor necrosis factor ?-dependent manner. J Infect Dis. 2014;210:1562-72 pubmed publisher
	Lauterbach N, Crivello P, Wieten L, Zito L, Groeneweg M, Voorter C, et al. Allorecognition of HLA-DP by CD4+ T cells is affected by polymorphism in its alpha chain. Mol Immunol. 2014;59:19-29 pubmed publisher
	Huizinga R, van Rijs W, Bajramovic J, Kuijf M, Laman J, Samsom J, et al. Sialylation of Campylobacter jejuni endotoxin promotes dendritic cell-mediated B cell responses through CD14-dependent production of IFN-? and TNF-?. J Immunol. 2013;191:5636-45 pubmed publisher
	Gonçalves R, Salmazi K, Santos B, Bastos M, Rocha S, Boscardin S, et al. CD4+ CD25+ Foxp3+ regulatory T cells, dendritic cells, and circulating cytokines in uncomplicated malaria: do different parasite species elicit similar host responses?. Infect Immun. 2010;78:4763-72 pubmed publisher
	Charles N, Hardwick D, Daugas E, Illei G, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med. 2010;16:701-7 pubmed publisher
	Fujita H, Nograles K, Kikuchi T, Gonzalez J, Carucci J, Krueger J. Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production. Proc Natl Acad Sci U S A. 2009;106:21795-800 pubmed publisher
	Zaba L, Cardinale I, Gilleaudeau P, Sullivan Whalen M, Suárez Fariñas M, Fuentes Duculan J, et al. Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses. J Exp Med. 2007;204:3183-94 pubmed

product information

Antigen :

HLA-DR

Apps. Abbrev. :

Flow Cytometry

Cat # :

307627

Clone :

L243

Item :

PerCP anti-human HLA-DR

Isotype :

Mouse IgG2a, κ

Other Names :

Major Histocompatibility Class II, MHC class II

Size :

25 tests

Price (USD) :

143 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PERCP

Application Notes :

The L243 monoclonal antibody reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. Clone L243 binds a conformational epitope on HLA-DRa which depends on the correct folding of the a heterodimer. 19 Additional reported applications (for the relevant formats) include: immunoprecipitation 8 , Western blotting 8 , in vitro blocking of mixed lymphocyte reactions 9,10 , depeletion of MHC class II cells 7 , immunohistochemical staining of acetone-fixed frozen sections 4,5 , and spatial biology (IBEX) 21,22 . For sensitive functional assays, we recommend using the Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) (Cat. No. 307648, 307665 - 307669).

more info or order :

BioLegend product webpage