APC anti-human CD262 (DR5, TRAIL-R2) | BioLegend 307408 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human CD262 (DR5, TRAIL-R2)

catalog :

307408

quantity :

100 tests

price :

350 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

DJR2-4 (7-8)

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 1b, 1e	Staniek J, Lorenzetti R, Heller B, Janowska I, Schneider P, Unger S, et al. TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes. Front Immunol. 2019;10:951 pubmed publisher
	Gabaev I, Williamson J, Crozier T, Schulz T, Lehner P. Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation. Cell Rep. 2020;33:108249 pubmed publisher
	Sztwiertnia I, Schenz J, Bomans K, Schaack D, Ohnesorge J, Tamulyte S, et al. Sevoflurane depletes macrophages from the melanoma microenvironment. PLoS ONE. 2020;15:e0233789 pubmed publisher
	Deng Y, Bi R, Guo H, Yang J, Du Y, Wang C, et al. Andrographolide Enhances TRAIL-Induced Apoptosis via p53-Mediated Death Receptors Up-Regulation and Suppression of the NF-кB Pathway in Bladder Cancer Cells. Int J Biol Sci. 2019;15:688-700 pubmed publisher
	Zhu Z, Liu J, Yang C, Li M, Wu R, Xiong Z. Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells. Cell Death Dis. 2019;10:118 pubmed publisher
	White C, Moesker B, Beliakova Bethell N, Martins L, Spina C, Margolis D, et al. Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model. PLoS Pathog. 2016;12:e1006026 pubmed publisher
	Lundqvist A, Abrams S, Schrump D, Alvarez G, Suffredini D, Berg M, et al. Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity. Cancer Res. 2006;66:7317-25 pubmed

product information

Antigen :

CD262

Apps. Abbrev. :

Flow Cytometry

Cat # :

307408

Clone :

DJR2-4 (7-8)

Item :

APC anti-human CD262 (DR5, TRAIL-R2)

Isotype :

Mouse IgG1, κ

Other Names :

TRAIL-R2, KILLER, TRICK2, TNFRSF10B, Ly98, CD262

Size :

100 tests

Price (USD) :

350 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC

Immunogen :

Extracellular domain of DR5-human IgG1 Fc fusion protein

Application Notes :

Additional reported applications (for the relevant formats) include: The DJR2-4 antibody is useful for immunofluorescent staining and flow cytometric analysis of DR5/TRAIL-R2 receptor expression. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 307406) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 307404) or biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).

more info or order :

BioLegend product webpage