PE anti-human CD262 (DR5, TRAIL-R2) | BioLegend 307405 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human CD262 (DR5, TRAIL-R2)

catalog :

307405

quantity :

25 tests

price :

134 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

DJR2-4 (7-8)

reactivity :

human, mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:200; loading ...; fig 1h	Jeong D, Kim H, Kim H, Kang M, Jung H, Oh Y, et al. Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2. elife. 2021;10: pubmed publisher
flow cytometry; human; loading ...; fig s2g	Chollat Namy M, Ben Safta Saadoun T, Haferssas D, Meurice G, Chouaib S, Thiery J. The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy. Cell Death Dis. 2019;10:695 pubmed publisher
flow cytometry; human; fig 4	Braun F, Mathur R, Sehgal L, Wilkie Grantham R, Chandra J, Berkova Z, et al. Inhibition of methyltransferases accelerates degradation of cFLIP and sensitizes B-cell lymphoma cells to TRAIL-induced apoptosis. PLoS ONE. 2015;10:e0117994 pubmed publisher
	Grayson K, Jyotsana N, Ortiz Otero N, King M. Overcoming TRAIL-resistance by sensitizing prostate cancer 3D spheroids with taxanes. PLoS ONE. 2021;16:e0246733 pubmed publisher
	Grayson K, Hope J, Wang W, Reinhart King C, King M. Taxanes Sensitize Prostate Cancer Cells to TRAIL-Induced Apoptotic Synergy via Endoplasmic Reticulum Stress. Mol Cancer Ther. 2021;20:833-845 pubmed publisher
	Ng W, Gong C, Yan X, Si G, Fang C, Wang L, et al. Targeting CD155 by rediocide-A overcomes tumour immuno-resistance to natural killer cells. Pharm Biol. 2021;59:47-53 pubmed publisher
	Wu Y, Kimura Y, Okamoto T, Matsuhisa K, Asada R, Saito A, et al. Inflammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation. Sci Rep. 2019;9:20301 pubmed publisher
	Brin E, Wu K, Dagostino E, Meng Chiang Kuo M, He Y, Shia W, et al. TRAIL stabilization and cancer cell sensitization to its pro-apoptotic activity achieved through genetic fusion with arginine deiminase. Oncotarget. 2018;9:36914-36928 pubmed publisher
	Yao C, Ni Z, Gong C, Zhu X, Wang L, Xu Z, et al. Rocaglamide enhances NK cell-mediated killing of non-small cell lung cancer cells by inhibiting autophagy. Autophagy. 2018;14:1831-1844 pubmed publisher
	Kolluri K, Alifrangis C, Kumar N, Ishii Y, Price S, Michaut M, et al. Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells. elife. 2018;7: pubmed publisher
	Vunnam N, Campbell Bezat C, Lewis A, Sachs J. Death Receptor 5 Activation Is Energetically Coupled to Opening of the Transmembrane Domain Dimer. Biophys J. 2017;113:381-392 pubmed publisher
	Choi Y, Lee J, Lee H, Chang D, Sung P, Jung M, et al. Liver injury in acute hepatitis A is associated with decreased frequency of regulatory T cells caused by Fas-mediated apoptosis. Gut. 2015;64:1303-13 pubmed publisher
	Magnussen G, Ree Rosnes A, Shahzidi S, Dong H, Emilsen E, Engesæter B, et al. Synthetic retinoid CD437 induces apoptosis and acts synergistically with TRAIL receptor-2 agonist in malignant melanoma. Biochem Biophys Res Commun. 2012;420:516-22 pubmed publisher
	Stolfi C, Caruso R, Franzè E, Rizzo A, Rotondi A, Monteleone I, et al. 2-methoxy-5-amino-N-hydroxybenzamide sensitizes colon cancer cells to TRAIL-induced apoptosis by regulating death receptor 5 and survivin expression. Mol Cancer Ther. 2011;10:1969-81 pubmed publisher
	Canestraro M, Galimberti S, Savli H, Palumbo G, Tibullo D, Nagy B, et al. Synergistic antiproliferative effect of arsenic trioxide combined with bortezomib in HL60 cell line and primary blasts from patients affected by myeloproliferative disorders. Cancer Genet Cytogenet. 2010;199:110-20 pubmed publisher

product information

Antigen :

CD262

Apps. Abbrev. :

Flow Cytometry

Cat # :

307405

Clone :

DJR2-4 (7-8)

Item :

PE anti-human CD262 (DR5, TRAIL-R2)

Isotype :

Mouse IgG1, κ

Other Names :

TRAIL-R2, KILLER, TRICK2, TNFRSF10B, Ly98, CD262

Size :

25 tests

Price (USD) :

134 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Immunogen :

Extracellular domain of DR5-human IgG1 Fc fusion protein

Application Notes :

Additional reported applications (for the relevant formats) include: The DJR2-4 antibody is useful for immunofluorescent staining and flow cytometric analysis of DR5/TRAIL-R2 receptor expression. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 307406) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 307404) or biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).

more info or order :

BioLegend product webpage