Purified anti-human CD262 (DR5, TRAIL-R2) | BioLegend 307302 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-human CD262 (DR5, TRAIL-R2)

catalog :

307302

quantity :

100 μg

price :

206 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DJR2-2 (2-6)

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 5

Reference
Winterberg D, Lenk L, O xdf wald M, Vogiatzi F, Gehlert C, Frielitz F, et al. Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo. J Clin Med. 2021;10: pubmed publisher
Vunnam N, Szymonski S, Hirsova P, Gores G, Sachs J, Hackel B. Noncompetitive Allosteric Antagonism of Death Receptor 5 by a Synthetic Affibody Ligand. Biochemistry. 2020;59:3856-3868 pubmed publisher
Mitchell M, Webster J, Chung A, Guimarães P, Khan O, Langer R. Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis. Nat Commun. 2017;8:14179 pubmed publisher
Sonnemann J, Trommer N, Becker S, Wittig S, Grauel D, Palani C, et al. Histone deacetylase inhibitor-mediated sensitization to TRAIL-induced apoptosis in childhood malignancies is not associated with upregulation of TRAIL receptor expression, but with potentiated caspase-8 activation. Cancer Biol Ther. 2012;13:417-24 pubmed publisher
Shi J, Tricot G, Garg T, Malaviarachchi P, Szmania S, Kellum R, et al. Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma. Blood. 2008;111:1309-17 pubmed

product information

Antigen :

CD262

Apps. Abbrev. :

Cat # :

307302

Clone :

DJR2-2 (2-6)

Item :

Purified anti-human CD262 (DR5, TRAIL-R2)

Isotype :

Mouse IgG1, κ

Other Names :

TRAIL-R2, KILLER, TRICK2, TNFRSF10B, Ly98, CD262

Size :

100 μg

Price (USD) :

206 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

Extracellular domain of DR5-human IgG1 Fc fusion protein

Application Notes :

For successful immunofluorescent staining results, it may be important to maximize signal over background by using a high sensitivity, three-layer staining technique (e.g., biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).;

more info or order :

BioLegend product webpage