APC anti-human CD261 (DR4, TRAIL-R1) | BioLegend 307208 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human CD261 (DR4, TRAIL-R1)

catalog :

307208

quantity :

100 tests

price :

332 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

DJR1

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 12

Reference
Menevse A, Ammer L, Vollmann Zwerenz A, Kupczyk M, Lorenz J, Weidner L, et al. TSPO acts as an immune resistance gene involved in the T cell mediated immune control of glioblastoma. Acta Neuropathol Commun. 2023;11:75 pubmed publisher
Lin C, Traets J, Vredevoogd D, Visser N, Peeper D. TSC2 regulates tumor susceptibility to TRAIL-mediated T-cell killing by orchestrating mTOR signaling. EMBO J. 2023;42:e111614 pubmed publisher
Volpin V, Michels T, Sorrentino A, Menevse A, Knoll G, Ditz M, et al. CAMK1D Triggers Immune Resistance of Human Tumor Cells Refractory to Anti-PD-L1 Treatment. Cancer Immunol Res. 2020;8:1163-1179 pubmed publisher
Liu H, Liang Z, Wang F, Zheng X, Zeng Z, He X, et al. Intestinal CD14+ Macrophages Protect CD4+ T Cells From Activation-induced Cell Death via Exosomal Membrane TNF in Crohn's Disease. J Crohns Colitis. 2020;14:1619-1631 pubmed publisher
Phalke S, Huang Y, Rubtsova K, Getahun A, Sun D, Reinhardt R, et al. γδ T cells shape memory-phenotype αβ T cell populations in non-immunized mice. PLoS ONE. 2019;14:e0218827 pubmed publisher
Zhu Z, Liu J, Yang C, Li M, Wu R, Xiong Z. Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells. Cell Death Dis. 2019;10:118 pubmed publisher
Brin E, Wu K, Dagostino E, Meng Chiang Kuo M, He Y, Shia W, et al. TRAIL stabilization and cancer cell sensitization to its pro-apoptotic activity achieved through genetic fusion with arginine deiminase. Oncotarget. 2018;9:36914-36928 pubmed publisher
Cordeau M, Belounis A, Lelaidier M, Cordeiro P, Sartelet H, Herblot S, et al. Efficient Killing of High Risk Neuroblastoma Using Natural Killer Cells Activated by Plasmacytoid Dendritic Cells. PLoS ONE. 2016;11:e0164401 pubmed publisher
Roybal K, Williams J, Morsut L, Rupp L, Kolinko I, Choe J, et al. Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors. Cell. 2016;167:419-432.e16 pubmed publisher
Burger J, Landau D, Taylor Weiner A, Bozic I, Zhang H, Sarosiek K, et al. Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition. Nat Commun. 2016;7:11589 pubmed publisher
Choi Y, Lee J, Lee H, Chang D, Sung P, Jung M, et al. Liver injury in acute hepatitis A is associated with decreased frequency of regulatory T cells caused by Fas-mediated apoptosis. Gut. 2015;64:1303-13 pubmed publisher
Malin D, Chen F, Schiller C, Koblinski J, Cryns V. Enhanced metastasis suppression by targeting TRAIL receptor 2 in a murine model of triple-negative breast cancer. Clin Cancer Res. 2011;17:5005-15 pubmed publisher

product information

Antigen :

CD261

Apps. Abbrev. :

Cat # :

307208

Clone :

DJR1

Item :

APC anti-human CD261 (DR4, TRAIL-R1)

Isotype :

Mouse IgG1, κ

Other Names :

TRAIL-R1, Apo-2, CD261, TNFRSF10A

Size :

100 tests

Price (USD) :

332 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC

Immunogen :

Extracellular domain of DR4-human IgG1 Fc fusion protein

Application Notes :

Additional reported applications (for the relevant formats) include: The DJR1 antibody is useful for immunofluorescent staining and flow cytometric analysis of DR4/TRAIL-R1 receptor expression. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 307206) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody or biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).;

more info or order :

BioLegend product webpage