APC anti-human CD261 (DR4, TRAIL-R1) | BioLegend 307207 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human CD261 (DR4, TRAIL-R1)

catalog :

307207

quantity :

25 tests

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

DJR1

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s4d	Roybal K, Williams J, Morsut L, Rupp L, Kolinko I, Choe J, et al. Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors. Cell. 2016;167:419-432.e16 pubmed publisher
	Henjum K, Arskog V, Jendresen C, Fladby T, Torp R, Nilsson L. Analyzing microglial-associated Aβ in Alzheimer's disease transgenic mice with a novel mid-domain Aβ-antibody. Sci Rep. 2020;10:10590 pubmed publisher
	Burrus C, McKinstry S, Kim N, Ozlu M, Santoki A, Fang F, et al. Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival. Cell Rep. 2020;30:642-657.e6 pubmed publisher
	Goldblatt D, Flores J, Valverde Ha G, Jaramillo A, Tkachman S, Kirkpatrick C, et al. Inducible epithelial resistance against acute Sendai virus infection prevents chronic asthma-like lung disease in mice. Br J Pharmacol. 2020;177:2256-2273 pubmed publisher
	Phalke S, Huang Y, Rubtsova K, Getahun A, Sun D, Reinhardt R, et al. γδ T cells shape memory-phenotype αβ T cell populations in non-immunized mice. PLoS ONE. 2019;14:e0218827 pubmed publisher
	Zhu Z, Liu J, Yang C, Li M, Wu R, Xiong Z. Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells. Cell Death Dis. 2019;10:118 pubmed publisher
	Brin E, Wu K, Dagostino E, Meng Chiang Kuo M, He Y, Shia W, et al. TRAIL stabilization and cancer cell sensitization to its pro-apoptotic activity achieved through genetic fusion with arginine deiminase. Oncotarget. 2018;9:36914-36928 pubmed publisher
	Cordeau M, Belounis A, Lelaidier M, Cordeiro P, Sartelet H, Herblot S, et al. Efficient Killing of High Risk Neuroblastoma Using Natural Killer Cells Activated by Plasmacytoid Dendritic Cells. PLoS ONE. 2016;11:e0164401 pubmed publisher
	Burger J, Landau D, Taylor Weiner A, Bozic I, Zhang H, Sarosiek K, et al. Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition. Nat Commun. 2016;7:11589 pubmed publisher
	Chandrasekaran S, Marshall J, Messing J, Hsu J, King M. TRAIL-mediated apoptosis in breast cancer cells cultured as 3D spheroids. PLoS ONE. 2014;9:e111487 pubmed publisher
	Choi Y, Lee J, Lee H, Chang D, Sung P, Jung M, et al. Liver injury in acute hepatitis A is associated with decreased frequency of regulatory T cells caused by Fas-mediated apoptosis. Gut. 2015;64:1303-13 pubmed publisher
	Sonnemann J, Trommer N, Becker S, Wittig S, Grauel D, Palani C, et al. Histone deacetylase inhibitor-mediated sensitization to TRAIL-induced apoptosis in childhood malignancies is not associated with upregulation of TRAIL receptor expression, but with potentiated caspase-8 activation. Cancer Biol Ther. 2012;13:417-24 pubmed publisher
	Malin D, Chen F, Schiller C, Koblinski J, Cryns V. Enhanced metastasis suppression by targeting TRAIL receptor 2 in a murine model of triple-negative breast cancer. Clin Cancer Res. 2011;17:5005-15 pubmed publisher
	Chen K, Chen H, Tai W, Feng W, Hsu C, Chen P, et al. Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells. J Pharmacol Exp Ther. 2011;337:155-61 pubmed publisher
	Lundqvist A, Abrams S, Schrump D, Alvarez G, Suffredini D, Berg M, et al. Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity. Cancer Res. 2006;66:7317-25 pubmed

product information

Antigen :

CD261

Apps. Abbrev. :

Flow Cytometry

Cat # :

307207

Clone :

DJR1

Item :

APC anti-human CD261 (DR4, TRAIL-R1)

Isotype :

Mouse IgG1, κ

Other Names :

TRAIL-R1, Apo-2, CD261, TNFRSF10A

Size :

25 tests

Price (USD) :

149 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC

Immunogen :

Extracellular domain of DR4-human IgG1 Fc fusion protein

Application Notes :

Additional reported applications (for the relevant formats) include: The DJR1 antibody is useful for immunofluorescent staining and flow cytometric analysis of DR4/TRAIL-R1 receptor expression. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 307206) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody or biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).

more info or order :

BioLegend product webpage