Purified anti-human CD261 (DR4, TRAIL-R1) | BioLegend 307201 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-human CD261 (DR4, TRAIL-R1)

catalog :

307201

quantity :

25 μg

price :

101 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DJR1

reactivity :

human

application :

western blot, flow cytometry

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s2g	Chollat Namy M, Ben Safta Saadoun T, Haferssas D, Meurice G, Chouaib S, Thiery J. The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy. Cell Death Dis. 2019;10:695 pubmed publisher
western blot; human; 1:2000	Chandrasekaran S, Marshall J, Messing J, Hsu J, King M. TRAIL-mediated apoptosis in breast cancer cells cultured as 3D spheroids. PLoS ONE. 2014;9:e111487 pubmed publisher
flow cytometry; human	Sullivan E, Jeha S, Kang G, Cheng C, Rooney B, Holladay M, et al. NK cell genotype and phenotype at diagnosis of acute lymphoblastic leukemia correlate with postinduction residual disease. Clin Cancer Res. 2014;20:5986-94 pubmed publisher
	Chen Q, Wang X, Luo F, Li N, Zhu N, Lu S, et al. HTNV Sensitizes Host Toward TRAIL-Mediated Apoptosis-A Pivotal Anti-hantaviral Role of TRAIL. Front Immunol. 2020;11:1072 pubmed publisher
	Yao C, Ni Z, Gong C, Zhu X, Wang L, Xu Z, et al. Rocaglamide enhances NK cell-mediated killing of non-small cell lung cancer cells by inhibiting autophagy. Autophagy. 2018;14:1831-1844 pubmed publisher
	Sonnemann J, Trommer N, Becker S, Wittig S, Grauel D, Palani C, et al. Histone deacetylase inhibitor-mediated sensitization to TRAIL-induced apoptosis in childhood malignancies is not associated with upregulation of TRAIL receptor expression, but with potentiated caspase-8 activation. Cancer Biol Ther. 2012;13:417-24 pubmed publisher
	Chen K, Chen H, Tai W, Feng W, Hsu C, Chen P, et al. Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells. J Pharmacol Exp Ther. 2011;337:155-61 pubmed publisher
	Lundqvist A, Abrams S, Schrump D, Alvarez G, Suffredini D, Berg M, et al. Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity. Cancer Res. 2006;66:7317-25 pubmed

product information

Antigen :

CD261

Apps. Abbrev. :

Flow Cytometry

Cat # :

307201

Clone :

DJR1

Item :

Purified anti-human CD261 (DR4, TRAIL-R1)

Isotype :

Mouse IgG1, κ

Other Names :

TRAIL-R1, Apo-2, CD261, TNFRSF10A

Size :

25 μg

Price (USD) :

101 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

Extracellular domain of DR4-human IgG1 Fc fusion protein

Application Notes :

Additional reported applications (for the relevant formats) include: The DJR1 antibody is useful for immunofluorescent staining and flow cytometric analysis of DR4/TRAIL-R1 receptor expression. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 307206) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody or biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).

more info or order :

BioLegend product webpage