product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human TCR α/β
catalog :
306717
quantity :
25 tests
price :
113 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
IP26
reactivity :
human
application :
flow cytometry
more info or order :
citations: 23
Reference
Lah S, Kim S, Kang I, Kim H, Hupperetz C, Jung H, et al. Engineering second-generation TCR-T cells by site-specific integration of TRAF-binding motifs into the CD247 locus. J Immunother Cancer. 2023;11: pubmed publisher
Lam D, Feliciano P, Arif A, Bohnuud T, Fernandez T, Gehrke J, et al. Improved cytosine base editors generated from TadA variants. Nat Biotechnol. 2023;41:686-697 pubmed publisher
Zhang Q, Yang J, Manoharan E, Yu A, Milone M. CRISPR/Cas9-mediated Gene Knockout Followed by Negative Selection Leads to a Complete TCR Depletion in ortho CAR19 T Cells. Bio Protoc. 2022;12: pubmed publisher
Ferry G, Agbuduwe C, Forrester M, Dunlop S, Chester K, Fisher J, et al. A Simple and Robust Single-Step Method for CAR-Vδ1 γδT Cell Expansion and Transduction for Cancer Immunotherapy. Front Immunol. 2022;13:863155 pubmed publisher
Anadon C, Yu X, Hänggi K, Biswas S, Chaurio R, Martin A, et al. Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells. Cancer Cell. 2022;40:545-557.e13 pubmed publisher
Durgin J, Thokala R, JOHNSON L, Song E, Leferovich J, Bhoj V, et al. Enhancing CAR T function with the engineered secretion of C. perfringens neuraminidase. Mol Ther. 2022;30:1201-1214 pubmed publisher
Warmuth S, Gunde T, Snell D, Brock M, Weinert C, Simonin A, et al. Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade. Oncoimmunology. 2021;10:2004661 pubmed publisher
Shen Y, Jiang L, Iyer V, Raposo B, Dubnovitsky A, Boddul S, et al. A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system. Comput Struct Biotechnol J. 2021;19:5360-5370 pubmed publisher
Wang Z, Li N, Feng K, Chen M, Zhang Y, Liu Y, et al. Phase I study of CAR-T cells with PD-1 and TCR disruption in mesothelin-positive solid tumors. Cell Mol Immunol. 2021;18:2188-2198 pubmed publisher
Bear A, Blanchard T, Cesare J, Ford M, Richman L, Xu C, et al. Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting. Nat Commun. 2021;12:4365 pubmed publisher
Japp A, Meng W, Rosenfeld A, Perry D, Thirawatananond P, Bacher R, et al. TCR+/BCR+ dual-expressing cells and their associated public BCR clonotype are not enriched in type 1 diabetes. Cell. 2021;184:827-839.e14 pubmed publisher
Congras A, Hoareau Aveilla C, Caillet N, Tosolini M, Villarese P, Cieslak A, et al. ALK-transformed mature T lymphocytes restore early thymus progenitor features. J Clin Invest. 2020;130:6395-6408 pubmed publisher
Lavaert M, Valcke B, Vandekerckhove B, Leclercq G, Liang K, Taghon T. Conventional and Computational Flow Cytometry Analyses Reveal Sustained Human Intrathymic T Cell Development From Birth Until Puberty. Front Immunol. 2020;11:1659 pubmed publisher
James K, Gomes T, Elmentaite R, Kumar N, Gulliver E, King H, et al. Distinct microbial and immune niches of the human colon. Nat Immunol. 2020;21:343-353 pubmed publisher
Oll Hurtado M, Wolbert J, Fisher J, Flutter B, Stafford S, Barton J, et al. Tumor infiltrating lymphocytes expanded from pediatric neuroblastoma display heterogeneity of phenotype and function. PLoS ONE. 2019;14:e0216373 pubmed publisher
Ahmed R, Omidian Z, Giwa A, Cornwell B, Majety N, Bell D, et al. A Public BCR Present in a Unique Dual-Receptor-Expressing Lymphocyte from Type 1 Diabetes Patients Encodes a Potent T Cell Autoantigen. Cell. 2019;177:1583-1599.e16 pubmed publisher
Montel Hagen A, Seet C, Li S, Chick B, Zhu Y, Chang P, et al. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019;24:376-389.e8 pubmed publisher
Omer B, Castillo P, Tashiro H, Shum T, Huynh M, Cardenas M, et al. Chimeric Antigen Receptor Signaling Domains Differentially Regulate Proliferation and Native T Cell Receptor Function in Virus-Specific T Cells. Front Med (Lausanne). 2018;5:343 pubmed publisher
Frasca D, Diaz A, Romero M, Thaller S, Blomberg B. Secretion of autoimmune antibodies in the human subcutaneous adipose tissue. PLoS ONE. 2018;13:e0197472 pubmed publisher
Rosskopf S, Leitner J, Paster W, Morton L, Hagedoorn R, Steinberger P, et al. A Jurkat 76 based triple parameter reporter system to evaluate TCR functions and adoptive T cell strategies. Oncotarget. 2018;9:17608-17619 pubmed publisher
Jiménez Reinoso A, Marin A, Subías M, López Lera A, Román Ortiz E, Payne K, et al. Human plasma C3 is essential for the development of memory B, but not T, lymphocytes. J Allergy Clin Immunol. 2017;: pubmed publisher
Fisher J, Abramowski P, Wisidagamage Don N, Flutter B, Capsomidis A, Cheung G, et al. Avoidance of On-Target Off-Tumor Activation Using a Co-stimulation-Only Chimeric Antigen Receptor. Mol Ther. 2017;25:1234-1247 pubmed publisher
Guo X, Dash P, CALVERLEY M, Tomchuck S, Dallas M, Thomas P. Rapid cloning, expression, and functional characterization of paired αβ and γδ T-cell receptor chains from single-cell analysis. Mol Ther Methods Clin Dev. 2016;3:15054 pubmed publisher
product information
Antigen :
TCR alpha/beta
Apps. Abbrev. :
FC
Cat # :
306717
Clone :
IP26
Item :
APC anti-human TCR α/β
Isotype :
Mouse IgG1, κ
Other Names :
α/β TCR, TCR α/β
Size :
25 tests
Price (USD) :
113 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Application Notes :
Additional reported applications (for the relevant formats) include: T cell activation. When co-staining with anti-CD3, we recommend using clone UCHT1, since we have confirmed that IP26 does not compete with this clone. Other anti-CD3 clones may compete out the binding of IP26.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA