product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human TCR α/β
catalog :
306708
quantity :
100 tests
price :
220 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
IP26
reactivity :
human
application :
flow cytometry
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:300; loading ...; fig s1a
Zhu L, Xie X, Zhang L, Wang H, Jie Z, Zhou X, et al. TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival. Nat Commun. 2018;9:2812 pubmed publisher
  • flow cytometry; human; fig s2e
Gee M, Han A, Lofgren S, Beausang J, Mendoza J, Birnbaum M, et al. Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes. Cell. 2018;172:549-563.e16 pubmed publisher
  • flow cytometry; human; 1:50; loading ...; fig 2a
Siegers G, Barreira C, Postovit L, Dekaban G. CD11d ?2 integrin expression on human NK, B, and ?? T cells. J Leukoc Biol. 2017;101:1029-1035 pubmed publisher
Le J, Park J, Ha V, Luong A, Branciamore S, Rodin A, et al. Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell Development. Immunity. 2020;52:1105-1118.e9 pubmed publisher
Frazzette N, Khodadadi Jamayran A, Doudican N, Santana A, Felsen D, Pavlick A, et al. Decreased cytotoxic T cells and TCR clonality in organ transplant recipients with squamous cell carcinoma. NPJ Precis Oncol. 2020;4:13 pubmed publisher
Fu S, He K, Tian C, Sun H, Zhu C, Bai S, et al. Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cells. Nat Commun. 2020;11:438 pubmed publisher
He J, Yang Q, Xiao Q, Lei A, Li X, Zhou P, et al. IRF-7 Is a Critical Regulator of Type 2 Innate Lymphoid Cells in Allergic Airway Inflammation. Cell Rep. 2019;29:2718-2730.e6 pubmed publisher
Sibener L, Fernandes R, Kolawole E, Carbone C, Liu F, McAffee D, et al. Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding. Cell. 2018;174:672-687.e27 pubmed publisher
Hunter S, Willcox C, Davey M, Kasatskaya S, Jeffery H, Chudakov D, et al. Human liver infiltrating γδ T cells are composed of clonally expanded circulating and tissue-resident populations. J Hepatol. 2018;69:654-665 pubmed publisher
Shan L, Deng K, Gao H, Xing S, Capoferri A, Durand C, et al. Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4+ T Cells Permissive for Latent HIV-1 Infection. Immunity. 2017;47:766-775.e3 pubmed publisher
Page K, Mezzalana E, Macdonald A, Zamuner S, De Nicolao G, van Maurik A. Temporal pharmacokinetic/pharmacodynamic interaction between human CD3ε antigen-targeted monoclonal antibody otelixizumab and CD3ε binding and expression in human peripheral blood mononuclear cell static culture. J Pharmacol Exp Ther. 2015;355:199-205 pubmed publisher
Renauer P, Coit P, Sawalha A. The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response. Clin Immunol. 2015;156:19-27 pubmed publisher
Chapman N, Connolly S, Reinl E, Houtman J. Focal adhesion kinase negatively regulates Lck function downstream of the T cell antigen receptor. J Immunol. 2013;191:6208-21 pubmed publisher
Siegers G, Felizardo T, Mathieson A, Kosaka Y, Wang X, Medin J, et al. Anti-leukemia activity of in vitro-expanded human gamma delta T cells in a xenogeneic Ph+ leukemia model. PLoS ONE. 2011;6:e16700 pubmed publisher
Pinto J, Dias V, Zoller H, Porto G, Carmo H, Carvalho F, et al. Hepcidin messenger RNA expression in human lymphocytes. Immunology. 2010;130:217-30 pubmed publisher
product information
Antigen :
TCR alpha/beta
Apps. Abbrev. :
Flow Cytometry
Cat # :
306708
Clone :
IP26
Item :
PE anti-human TCR α/β
Isotype :
Mouse IgG1, κ
Other Names :
α/β TCR, TCR α/β
Size :
100 tests
Price (USD) :
220 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Application Notes :
Additional reported applications (for the relevant formats) include: T cell activation. When co-staining with anti-CD3, we recommend using clone UCHT1, since we have confirmed that IP26 does not compete with this clone. Other anti-CD3 clones may compete out the binding of IP26.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA