Purified anti-human CD184 (CXCR4) (Maxpar® Ready) | BioLegend 306523 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-human CD184 (CXCR4) (Maxpar® Ready)

catalog :

306523

quantity :

100 μg

price :

218 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

12G5

reactivity :

human, mouse, rhesus macaque

application :

immunocytochemistry, flow cytometry, other, mass cytometry

more info or order :

BioLegend product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
mass cytometry; human; 500 ug/ml; loading ...; fig s11a	Helmink B, Reddy S, Gao J, Zhang S, Basar R, Thakur R, et al. B cells and tertiary lymphoid structures promote immunotherapy response. Nature. 2020;577:549-555 pubmed publisher
flow cytometry; human; loading ...; fig st1	Cerboni S, Jeremiah N, Gentili M, Gehrmann U, Conrad C, Stolzenberg M, et al. Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes. J Exp Med. 2017;214:1769-1785 pubmed publisher
flow cytometry; human; 1:100; loading ...; fig s4b immunocytochemistry; human; 1:50; loading ...; fig s3a	Smith N, Pietrancosta N, Davidson S, Dutrieux J, Chauveau L, Cutolo P, et al. Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement. Nat Commun. 2017;8:14253 pubmed publisher
flow cytometry; human; tbl 3	Fromm J, Thomas A, Wood B. Characterization and Purification of Neoplastic Cells of Nodular Lymphocyte Predominant Hodgkin Lymphoma from Lymph Nodes by Flow Cytometry and Flow Cytometric Cell Sorting. Am J Pathol. 2017;187:304-317 pubmed publisher
flow cytometry; human; loading ...; tbl 1	Sumatoh H, Teng K, Cheng Y, Newell E. Optimization of mass cytometry sample cryopreservation after staining. Cytometry A. 2017;91:48-61 pubmed publisher
flow cytometry; human; loading ...; fig 3a	Gadd V, Patel P, Jose S, Horsfall L, Powell E, Irvine K. Altered Peripheral Blood Monocyte Phenotype and Function in Chronic Liver Disease: Implications for Hepatic Recruitment and Systemic Inflammation. PLoS ONE. 2016;11:e0157771 pubmed publisher
flow cytometry; human; 2 ug/ml; fig 5b	Kamiyama D, Sekine S, Barsi Rhyne B, Hu J, Chen B, Gilbert L, et al. Versatile protein tagging in cells with split fluorescent protein. Nat Commun. 2016;7:11046 pubmed publisher
flow cytometry; human; loading ...; fig 2	Jost T, Borga C, Radaelli E, Romagnani A, Perruzza L, Omodho L, et al. Role of CXCR4-mediated bone marrow colonization in CNS infiltration by T cell acute lymphoblastic leukemia. J Leukoc Biol. 2016;99:1077-87 pubmed publisher
flow cytometry; mouse; fig 4c	Levit Zerdoun E, Becker M, Pohlmeyer R, Wilhelm I, Maity P, Rajewsky K, et al. Survival of IgÎ±-Deficient Mature B Cells Requires BAFF-R Function. J Immunol. 2016;196:2348-60 pubmed publisher
other; human; loading ...; fig st1	Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
flow cytometry; human; 1:200; fig s4	Adoro S, Cubillos Ruiz J, Chen X, Deruaz M, Vrbanac V, Song M, et al. IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection. Nat Commun. 2015;6:7562 pubmed publisher
flow cytometry; human; fig 3	Zsiros E, Duttagupta P, Dangaj D, Li H, Frank R, Garrabrant T, et al. The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy. Clin Cancer Res. 2015;21:2840-50 pubmed publisher
flow cytometry; human; loading ...; fig 2f	van der Waart A, van de Weem N, Maas F, Kramer C, Kester M, Falkenburg J, et al. Inhibition of Akt signaling promotes the generation of superior tumor-reactive T cells for adoptive immunotherapy. Blood. 2014;124:3490-500 pubmed publisher
flow cytometry; human	Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
	Jordan S, Tung N, Casanova Acebes M, Chang C, Cantoni C, Zhang D, et al. Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool. Cell. 2019;178:1102-1114.e17 pubmed publisher
	Wostradowski T, Gudi V, Pul R, Gingele S, Lindquist J, Stangel M, et al. Effect of interferon-Î²1b on CXCR4-dependent chemotaxis in T cells from multiple sclerosis patients. Clin Exp Immunol. 2015;182:162-72 pubmed publisher
	Isnardi I, Ng Y, Menard L, Meyers G, Saadoun D, Srdanovic I, et al. Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Blood. 2010;115:5026-36 pubmed publisher
	Thompson B, Jin Y, Wu K, Colvin R, Luster A, Birnbaumer L, et al. Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling. J Biol Chem. 2007;282:9547-55 pubmed

product information

Antigen :

CD184

Apps. Abbrev. :

FC, CyTOF®

Cat # :

306523

Clone :

12G5

Item :

Purified anti-human CD184 (CXCR4) (Maxpar® Ready)

Isotype :

Mouse IgG2a, κ

Other Names :

CXCR4, Fusin

Size :

100 μg

Price (USD) :

218 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PUREMAX

Immunogen :

CP-MAC-infected Sup-T1 cells

Application Notes :

Additional reported applications (for the relevant formats) include: immunohistochemical staining of paraffin-embedded tissue sections^11, immunocytochemistry^3, immunofluorescence microscopy^2,6, and blocking of CD4-independent infection by HIV-2 and CD4-dependent infection by some T cell-tropic isolates of HIV-1^4,5. Clone 12G5 may not be suitable for Western blotting.^10 The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 306539 & 306540).;

more info or order :

BioLegend product webpage