product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-human CD184 (CXCR4)
catalog :
306518
quantity :
100 tests
price :
413 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV421
clone name :
12G5
reactivity :
human, mouse, rhesus macaque
application :
flow cytometry
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 4c
Levit Zerdoun E, Becker M, Pohlmeyer R, Wilhelm I, Maity P, Rajewsky K, et al. Survival of Igα-Deficient Mature B Cells Requires BAFF-R Function. J Immunol. 2016;196:2348-60 pubmed publisher
  • flow cytometry; human
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed publisher
Gage B, Liu J, Innes B, Macparland S, McGilvray I, Bader G, et al. Generation of Functional Liver Sinusoidal Endothelial Cells from Human Pluripotent Stem-Cell-Derived Venous Angioblasts. Cell Stem Cell. 2020;27:254-269.e9 pubmed publisher
Shook B, Wasko R, Mano O, Rutenberg Schoenberg M, Rudolph M, Zirak B, et al. Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair. Cell Stem Cell. 2020;26:880-895.e6 pubmed publisher
Hinks T, Marchi E, Jabeen M, Olshansky M, Kurioka A, Pediongco T, et al. Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality. Cell Rep. 2019;28:3249-3262.e5 pubmed publisher
Shao Y, Chen J, Dong L, He X, Cheng R, Zhou K, et al. A Protective Effect of PPARα in Endothelial Progenitor Cells Through Regulating Metabolism. Diabetes. 2019;68:2131-2142 pubmed publisher
Mair B, Tomic J, Masud S, Tonge P, Weiss A, Usaj M, et al. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies. Cell Rep. 2019;27:599-615.e12 pubmed publisher
Smulski C, Küry P, Seidel L, Staiger H, Edinger A, Willen L, et al. BAFF- and TACI-Dependent Processing of BAFFR by ADAM Proteases Regulates the Survival of B Cells. Cell Rep. 2017;18:2189-2202 pubmed publisher
Xu J, Liang J, Meng Y, Yan J, Yu X, Liu C, et al. Vascular CXCR4 Expression Promotes Vessel Sprouting and Sensitivity to Sorafenib Treatment in Hepatocellular Carcinoma. Clin Cancer Res. 2017;23:4482-4492 pubmed publisher
Saxena S, Ronn R, Guibentif C, Moraghebi R, Woods N. Cyclic AMP Signaling through Epac Axis Modulates Human Hemogenic Endothelium and Enhances Hematopoietic Cell Generation. Stem Cell Reports. 2016;6:692-703 pubmed publisher
Demberg T, Mohanram V, Venzon D, Robert Guroff M. Phenotypes and distribution of mucosal memory B-cell populations in the SIV/SHIV rhesus macaque model. Clin Immunol. 2014;153:264-76 pubmed publisher
Tabler C, Lucera M, Haqqani A, MCDONALD D, Migueles S, Connors M, et al. CD4+ memory stem cells are infected by HIV-1 in a manner regulated in part by SAMHD1 expression. J Virol. 2014;88:4976-86 pubmed publisher
Isnardi I, Ng Y, Menard L, Meyers G, Saadoun D, Srdanovic I, et al. Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Blood. 2010;115:5026-36 pubmed publisher
Thompson B, Jin Y, Wu K, Colvin R, Luster A, Birnbaumer L, et al. Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling. J Biol Chem. 2007;282:9547-55 pubmed
product information
Antigen :
CD184
Apps. Abbrev. :
FC
Cat # :
306518
Clone :
12G5
Item :
Brilliant Violet 421™ anti-human CD184 (CXCR4)
Isotype :
Mouse IgG2a, κ
Other Names :
CXCR4, Fusin
Size :
100 tests
Price (USD) :
413 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV421
Immunogen :
CP-MAC-infected Sup-T1 cells
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of paraffin-embedded tissue sections^11, immunocytochemistry^3, immunofluorescence microscopy^2,6, and blocking of CD4-independent infection by HIV-2 and CD4-dependent infection by some T cell-tropic isolates of HIV-1^4,5. Clone 12G5 may not be suitable for Western blotting.^10 The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 306539 & 306540).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA